Communicore Animal Facility (CAF) Renovation Phase III Part II

Communicore 动物设施 (CAF) 改造第三期第二部分

• 批准号: 7248297
• 负责人: AUGUST H BATTLES
• 金额: $ 70万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2009-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7248297
• 关键词: Accreditation; Address; Air Conditioning; Animal Housing; Animal Welfare; Animals; Area; Biohazardous Substance; Biomedical Research; Book Chapters; Commit; Communities; Complex; Consult; Consultations; Decontamination; Development; Doctor of Veterinary Medicine; Ensure; Environment; Environmental Health; Environmental air flow; Facility Designs; Florida; Funding; Health Sciences; Heating; Hydrogen Peroxide; International; Laboratories; Laboratory Animals; Laboratory Research; Methods; Monitor; Operative Surgical Procedures; Phase; Plants; Preparation; Process; Quality of Care; Quarantine; Research; Rodent Diseases; Route; Safety; Science; Services; Staging; Sterility; Sterilization for infection control; Surface; System; United States National Institutes of Health; Universities; Workplace; animal care; animal facility; animal resource; authority; base; building design; design; digital; experience; facility renovation; foot; improved; pressure; programs; vapor

DESCRIPTION (provided by applicant): In 2001 The University of Florida initiated a 10 year plan to improve, enlarge and centralize its animal resource program to provide the best possible environment for scientific inquiry, quality care to laboratory animals, and a safe work environment while ensuring conformity with the Animal Welfare Act and the Guide. This proposal describes a three-phase plan to modernize the largest existing animal facility, the Communicore Animal Facility (CAF), and further centralize the animal resource program. Phase I replaced the worn out (>30yr old) heating, ventilation, and air conditioning (HVAC) supply units of CAF but could not address the distribution and control deficiencies of the system. Phase II is in the planning stage and will construct a 62,000 gross square feet (gsf) addition to CAF as part of a 172,000 gsf Biomedical Sciences Building immediately adjacent to CAF. Phase III has three parts based on the aea served by the existing HVAC system. Phase III will replace the remainder of the worn out HVAC and reconfigure CAF. Planning for Part I which will enlarge and modernize the CAF ABSL3 suite is underway. Part 3 will renovate the east half of CAF and will be done last. This proposal is Part 2 of Phase III and will replace the portion of the worn out HVAC system that serves about 22,750 gsf of the CAF with a modern fully redundant HVAC system with digital controls and monitoring, utilizing self regulating pressure independent valves. In addition, the central surgery will be reconfigured to provide a restricted area with a prep room and surgery dedicated for animals with biohazards. The quarantine area will be reconfigured to provide an exit for potentially infectious caging and materials and their efficient decontamination. Additionally, the route of sterile caging into the ABSL3 from the new CAF Annex cage wash will be shortened by providing a new entrance and method for sterilizing incoming caging and material in an efficient manner. All large animal rooms, surgical suites, animal prep rooms and the quarantine and ABSL3 entrances will be constructed to utilize vapor phase hydrogen peroxide sterilization. Electrical service in animal rooms and the surgical suite will be upgraded. We propose partial funding of this project with the University providing $5.12 for each $1.00 requested from NIH.

描述（由申请人提供）： 2001 年，佛罗里达大学启动了一项十年计划，旨在改进、扩大和集中其动物资源计划，为科学探究、实验动物优质护理和安全的工作环境提供最佳环境，同时确保符合《动物福利法》和《指南》。该提案描述了一项三阶段计划，旨在对现有最大的动物设施 Communicore 动物设施 (CAF) 进行现代化改造，并进一步集中动物资源计划。第一阶段更换了 CAF 磨损的（>30 年）供暖、通风和空调 (HVAC) 供应装置，但无法解决系统的分配和控制缺陷。第二阶段正处于规划阶段，将在 CAF 上建造 62,000 总平方英尺 (gsf) 的扩建项目，作为紧邻 CAF 的 172,000 总平方英尺生物医学科学大楼的一部分。第三期根据现有暖通空调系统服务的区域分为三个部分。第三阶段将更换剩余的破旧 HVAC 并重新配置 CAF。第一部分的规划正在进行中，该部分将扩大和现代化 CAF ABSL3 套件。第 3 部分将改造 CAF 的东半部，并将在最后完成。 该提案是第三阶段的第二部分，将用具有数字控制和监控功能的现代完全冗余 HVAC 系统取代服务于 CAF 约 22,750 gsf 的破旧 HVAC 系统部分，并利用自调节压力独立阀。此外，中央手术室将进行重新配置，以提供一个带有准备室的禁区和专门用于有生物危害的动物的手术室。检疫区将被重新配置，为可能具有传染性的笼子和材料及其有效净化提供出口。此外，通过提供新的入口和方法，以有效的方式对进入的笼具和材料进行消毒，从新的 CAF 附件笼具清洗进入 ABSL3 的无菌笼具路线将缩短。所有大型动物室、手术室、动物准备室以及检疫和 ABSL3 入口都将采用气相过氧化氢灭菌。动物室和手术室的电力服务将得到升级。我们建议大学为该项目提供部分资助，每向 NIH 申请 1 美元，大学提供 5.12 美元。