Characterization of the HCV NS5A Protein

HCV NS5A 蛋白的表征

• 批准号: 7280770
• 负责人: TIMOTHY TELLINGHUISEN
• 金额: $ 10.8万
• 依托单位: SCRIPPS RESEARCH INSTITUTE, THE
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-01 至 2008-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7280770
• 关键词: Acids; Area; Binding; Biochemical; Biochemical Genetics; Biological Assay; Cirrhosis; Class; Consensus; Crystallization; Data; Disease; Disulfides; Evaluation; Evolution; GB virus C; Glean; Goals; Hepatitis; Hepatitis C virus; Human; Maps; Membrane; Methodology; Methods; Molecular; Mutagenesis; Nucleic Acid Binding; Nucleic Acids; Numbers; Object Attachment; Patients; Population; Process; Property; Protein Binding; Protein Region; Proteins; RNA; RNA Binding; RNA Helicase; RNA Sequences; RNA chemical synthesis; RNA replication; Regulation; Replicon; Research; Research Personnel; Site; Solutions; Specificity; Structure; Surface; System; Testing; Tin; Treatment Protocols; Viral; abstracting; analytical ultracentrifugation; base; concept; dimer; disulfide bond; hepatitis C virus NS-5A protein; inhibitor/antagonist; interest; mutant; novel; nucleic acid binding protein; pathogen; programs; protein protein interaction; protein purification; replicase

ABSTRACT NOT PROVIDED

未提供摘要

项目成果

Regulation of hepatitis C virion production via phosphorylation of the NS5A protein.

通过NS5A蛋白的磷酸化来调节丙型肝炎的产生。

• DOI: 10.1371/journal.ppat.1000032
• 发表时间: 2008-03-21
• 期刊: PLOS PATHOGENS
• 影响因子: 6.7
• 作者: Tellinghuisen, Timothy L.;Foss, Katie L.
• 通讯作者: Foss, Katie L.