Postdoctoral Training in Renal Diseases and Hypertension

描述(申请人提供)：肾脏疾病和高血压是主要的、日益严重的公共卫生问题，被列为“2010年健康人”议程的目标。国家担心，新培训的有能力在这些领域取得重大进展和发挥领导作用的学术科学家的数量将不足。因此，肾脏疾病和高血压奖学金培训计划是德克萨斯大学休斯顿健康科学中心学术部门的优秀教师共同努力的成果，旨在为杰出的、以学术为导向的博士后研究员提供肾脏疾病和高血压方面的强化基础或临床研究培训。一个由资深科学家和内科科学家组成的富有成效和协作的小组具有互补的兴趣，并表现出对指导和培训的承诺，将作为四名博士后研究员的指导教师。学院实验室在肾脏病和高血压的重要领域提供研究经验，包括上皮运输生理学和生物学、血管和肾细胞信号转导、血管生物学、免疫介导的损伤、组织限制性基因表达、治疗高血压的人类临床试验以及人类高血压和糖尿病的遗传学和药物基因组学。该计划提供基础和最新学科的培训和教学指导，包括分子、细胞和结构生物学、分子遗传学、生物化学、转基因技术、电生理学、免疫学、功能基因组学、基因传递、生物计量学和流行病学。受训人员还将受益于德克萨斯医疗中心的大量资源和该地区大量的高危或受影响的患者。所有被该计划录取的申请者必须坚定地致力于学术研究事业和培训计划的目标。拥有医学博士学位的学员将参加一个项目，包括一年的临床培训，这不是由这项拨款支持的，以及至少两年的研究培训，由这项申请的资金支持。博士申请者将被要求具有以前的研究经验，可以是非肾脏领域的，并且有出色的推荐信。所有受训人员将被要求参加涉及研究方法、实验设计、研究完整性和伦理学的特定课程。来自不同背景的受训人员的代表将受到重视和鼓励。该计划的目标是，其毕业生将为新一代学术肾病学家和肾脏研究人员做出贡献，以应对肾脏疾病和高血压方面的挑战性问题

DESCRIPTION (provided by applicant):Kidney disease and hypertension are major, growing public health problems that are targeted in the "Health People 2010" agenda. There is national concern that the number of newly trained academic scientists equipped to make major advances and to assume leadership roles in these areas will be inadequate. Accordingly, the Fellowship Training Program in Renal Diseases and Hypertension represents a cooperative effort of accomplished faculty from the academic components of The University of Texas Health Science Center at Houston to provide to outstanding, academically-oriented postdoctoral fellows intensive basic or clinical research training in renal disorders and hypertension. A productive and collaborative group of senior scientists and physician-scientists with complementary interests and a demonstrated commitment to mentorship and training will serve as mentoring faculty to four postdoctoral fellows. The faculty laboratories offer research experience in important areas of nephrology and hypertension, including, epithelial transport physiology and biology, vascular and renal cell signaling, vascular biology, immunologically mediated injury, tissue-restricted gene expression, human clinical trials in the treatment of hypertension, and the genetics and pharmacogenomics of human hypertension and diabetes. The program provides training and didactic instruction in fundamental and state-of-the-art disciplines, including molecular, cell, and structural biology, molecular genetics, biochemistry, transgenic technologies, electrophysiology, immunology, functional genomics, gene delivery, biometry, and epidemiology. The trainees will also profit from the substantial resources of the Texas Medical Center and the enormous population of at-risk or affected patients in the area. All applicants accepted into the program must have a firm commitment to a career in academic investigation and to the goals of the Training Program. Trainees with M.D. degrees will pursue a program consisting of one year of clinical training, which is not supported by this grant, and at least two years of research training to be supported by funds from this application. Ph.D. applicants will be required to have prior research experience, which can be in non-renal fields, and outstanding references. All trainees will be required to attend specific courses addressing research methodology, experimental design, research integrity, and ethics. Representation by trainees from diverse backgrounds will be valued and encouraged. It is the goal of the Program that its graduates will contribute to a new generation of academic nephrologists and renal investigators equipped to address the challenging problems in renal diseases and hypertension