Training Program in Chemosensory Neuroscience

描述(申请人提供)：过去十年经历了惊人的增长 在化学感官研究和对这一重要性的日益认识中 菲尔德。味觉和嗅觉系统提供了独特的机会来解决 神经生物学中的基本问题。对化学感官的研究范围从 嗅觉和味觉感受器的分子生物学研究 嗅觉和味觉功能障碍的治疗。令人兴奋的发现是 从应用新的和快速变化的技术和许多 博士后研究人员正在从其他学科进入这一领域。这些 研究人员带来了分子生物学的技术和方法， 发展神经科学、生物物理学、临床医学等学科 研究化学意义上的问题。比以往任何时候，它都是 重要的是保持多学科培训计划，以提供这些 拥有该领域基本知识的科学家，这将使他们能够更多地 清楚而准确地指导和解释他们的研究。此应用程序寻求 再次支持对四名博士后研究员进行研究培训。这个 培训教师在化学感官方面有完善的研究计划 以及神经科学的相关领域，这些领域得到了美国国立卫生研究院和其他机构的大力资助 经纪公司。这些教员使用的技术范围很广，包括 分子，电生理，超微结构，神经化学， 药理学、免疫学和心理物理学，使用的制剂范围 从体外组织培养和切片到行为动物。除了……之外 实验室研究培训，博士后研究员每两周参加一次 化学感觉杂志俱乐部和来访神经学家的定期研讨会系列 在化学感官和其他领域。除一名培训人员外，所有培训人员都是 设在解剖和神经生物学系，那里有一个主要的关注点 化学感官研究。这个组织有训练许多人的既定记录 化学感官和其他神经科学领域的杰出研究人员。 在本供资期间得到支助的8名博士后研究员 非常有成效；有三个人已经进入终身教职轨道。这个 培训教师是神经科学跨学科项目的一部分，该项目 由解剖学和神经生物学主席执导。解剖学与学部 神经生物学围绕新配备的核心实验室进行组织，这些实验室提供 与学生和博士后研究员高度互动和 分享设备、技术和想法。这是这位教师的力量所在， 他们广泛的实验方法，以及他们高度的 智能协作，提供独特且令人兴奋的多学科 化学意义的博士后研究员培训计划。

DESCRIPTION (provided by applicant): The last decade has seen spectacular growth in chemosensory research and increased recognition of the importance of this field. The taste and olfactory systems provide unique opportunities to address fundamental issues in neurobiology. Research in the chemical senses ranges from the molecular biology of olfactory and taste receptors to the identification and treatment of olfactory and gustatory dysfunction. Exciting discoveries are emerging from the application of new and rapidly changing technologies and many postdoctoral researchers are entering this field from other disciplines. These investigators bring the techniques and approaches of molecular biology, developmental neuroscience, biophysics, clinical medicine, and other disciplines to research issues in the chemical senses. More than ever before, it is important to maintain multidisciplinary training programs that can provide these scientists with the basic knowledge of this field, which will allow them to more clearly and precisely direct and interpret their studies. This application seeks to renew support for research training for four postdoctoral fellows. The training faculty have well-established research programs in the chemical senses and related areas of neuroscience, which are heavily funded by the NIH and other agencies. These faculty employ a wide spectrum of techniques, including molecular, electrophysiological, ultrastructural, neurochemical, pharmacological, immunological, and psychophysical, using preparations ranging from in vitro tissue culture and slices to behaving animals. In addition to laboratory research training, postdoctoral fellows participate in a biweekly Chemosensory Journal Club and regular seminar series by visiting neuroscientists in the chemical senses and other areas. All but one of the training faculty are housed in the Department of Anatomy & Neurobiology, where there is a major focus on chemosensory research. This group has an established record of training many outstanding researchers in the chemical senses and other areas of neuroscience. The eight postdoctoral fellows supported during the current funding period have been very productive; three have moved into tenure-track faculty positions. The training faculty are part of an interdisciplinary Program in Neuroscience, which is directed by the Chair of Anatomy & Neurobiology. The Department of Anatomy & Neurobiology is organized around newly equipped core laboratories, which provide the students and postdoctoral fellows with a high degree of interaction and sharing of equipment, techniques and ideas. It is the strength of this faculty, their wide range of experimental approaches, and their high degree of intellectual collaboration that provides a unique and exciting multidisciplinary training program for postdoctoral fellows in the chemical senses.