Advancing Research Operations at an Emergent R1 Minority-Serving Institution

推进新兴 R1 少数族裔服务机构的研究运作

• 批准号: 10734698
• 负责人: Douglas M Watts
• 金额: $ 19.87万
• 依托单位: UNIVERSITY OF TEXAS EL PASO
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10734698
• 关键词: Achievement; Animal Experimentation; Animal Housing; Animal Husbandry; Animal Welfare; Animals; Biological Sciences; Biology; Biomedical Engineering; Biomedical Research; Birds; Caring; Censuses; Communicable Diseases; Controlled Environment; Dedications; Ecology; Education; Educational process of instructing; Ensure; Equipment; Facility Designs; Faculty; Failure; Floor; Fostering; Goals; Growth; Guidelines; Health; Health Disparities Research; Housing; IACUC; Inbred BALB C Mice; Inbred Strain; Infrastructure; Institution; Institutional Policy; Interdisciplinary Study; Knowledge; Laboratory Animals; Laws; Learning; Life Expectancy; Maintenance; Malignant Neoplasms; Mammals; Medical; Microtus; Minority; Minority-Serving Institution; Mission; Modernization; Monitor; Mus; National Institute on Minority Health and Health Disparities; Needs Assessment; Neurosciences; Operations Research; Outcome; Performance; Productivity; Psychology; Public Health; Publications; Rattus; Reptiles; Research; Research Activity; Research Infrastructure; Research Peer Review; Research Personnel; Research Project Grants; Research Support; Resources; Rodent; Services; Site; Students; Texas; Transgenic Mice; Universities; Water; Zebrafish; animal care; animal facility; animal resource; aquarium; college; community engagement; design; expiration; imaging study; imaging system; in vivo imaging system; mouse model; operation; prairie vole; programs; repaired; research study

Project Abstract. The University of Texas at El Paso (UTEP) is a minority-serving academic institution whose mission is dedicated to the advancement of knowledge through research, education, community engagement, as an emergent national research institution. At UTEP, there is a critical need for equipment to enhance our research infrastructure and maintain our status as an R1 institute in the years to come. and public service. Our designation as a Carnegie Tier One university "R1: Doctoral Universities – very high research activity" distinguishes UTEP As a premier biomedical research institution that is heavily engaged in promoting diversity in the scientific workforce, the proposed project will add a critically needed cage/rack washer in our Biosciences Main animal facility. The proposed request will foster our robust and productive biomedical research program involving laboratory animals. The UTEP biomedical research program is being supported by the Department of Laboratory Animal Resources Center (LARC) in partnership with the Institutional Animal Care and Use Committee (IACUC). The LARC manages and monitors the housing and use of research animals to ensure compliance with applicable Federal, State, and Local laws and guidelines as well as Institutional Policy. The LARC supports the Main animal facility in the Biosciences building, and the 3 additional animal satellite facilities in Psychology, Biology and the Interdisciplinary Research Building (IDRB). Their oversight also includes our Zebra fish aquarium as well as 2 field research stations located off of our main campus. The animal facilities are designed to accommodate exquisitely controlled environments and equipment for the maintenance and care and use of laboratory animals. In a comprehensive assessment of needs and projected growth, we identified a critical need for a cage/rack washer in the Biosciences Main animal facility. The current washer has been in use for more than 10 years, and has exceeded its 10-year life expectancy. This washer is critical to our operations because it provides sanitizing services for equipment used in the Main animal facility as well as for research involving animals housed in the Biology and Psychology animal facilities. The sanitizing services in the newly established IDRB facility is being supported by its own washer that provides services for 3 investigators and their 3 projects as well as being used as a back-up washer for the one in the Main animal facility due to frequent malfunctioning. Therefore, the requested upgraded cage/rack washer will support 39 of 42 active biomedical research projects involving the use of prairie voles (Microtus ochrogaster), mice (Mus species) BALB/c, C57/BL6 and transgenic mice, and rats (Rattus species), Sprague-Dawley and Wistar strains. The 39 projects are being conducted by 25 UTEP faculty from 5 different colleges related to public-health problems in the neurosciences, infectious diseases, cancer, and ecology and evolutionary biology, and biomedical engineering. The upgraded cage/rack washer will provide the support required to sustain the animal care and use program essential for supporting the UTEP's robust and productive biomedical research programs. 1

项目摘要。德克萨斯大学埃尔帕索分校（UTEP）是一家少数族裔的学术机构 使命致力于通过研究，教育，社区参与， 作为紧急国家研究机构。在UTEP，有一个关键 多年来，需要设备来增强我们的研究基础设施并保持我们作为R1研究所的地位 来。 和公共服务。我们作为卡内基一级大学的设计“ R1：博士大学 - 非常高 研究活动“区分UTEP 作为一家主要的生物医学研究机构，大量参与促进多样性 科学劳动力，拟议的项目将在我们的生物科学中添加迫切需要的笼子/架子洗衣机 动物设施。拟议的请求将促进我们涉及的强大而富有成效的生物医学研究计划 实验动物。 UTEP生物医学研究计划得到了实验室的支持 动物资源中心（LARC）与机构动物护理和使用委员会（IACUC）合作。 LARC管理和监视研究动物的住房和使用，以确保符合适用的 联邦，州和地方法律和准则以及机构政策。 LARC支持主要动物 生物科学大楼中的设施，以及心理学，生物学和生物学的另外三个动物卫星设施 跨学科研究大楼（IDRB）。他们的监督还包括我们的斑马鱼水族馆以及2 现场研究站位于我们主校园外。动物设施旨在容纳 精心控制的环境和设备，用于维护，保养和使用实验室动物。 在对需求和预计增长的全面评估中，我们确定了对笼子/机架的关键需求 洗衣机在生物科学的主要动物设施中。当前的洗衣机已经使用了10多年，并且 超出了其10年的预期寿命。这对我们的操作至关重要，因为它提供了消毒 用于主要动物设施中使用的设备以及涉及所在动物的研究 生物学和心理学动物设施。新成立的IDRB设施中的消毒服务正在 由其自己的洗衣机支持，该洗衣机为3个调查人员及其3个项目提供服务，并被使用 由于经常出现故障，作为主要动物设施中的备用洗衣机。因此， 要求升级的笼子/机架垫圈将支持42个活跃的生物医学研究项目中的39个涉及使用 草原田鼠（Microtus ochrogaster），小鼠（MUS种）BALB/C，C57/BL6和转基因小鼠以及大鼠（Rattus） 物种），Sprague-Dawley和Wistar菌株。这39个项目由25个UTEP教职员工进行。 与神经科学，传染病，癌症和生态学的公共卫生问题有关的不同学院 和进化生物学和生物医学工程。升级的笼子/机架垫圈将提供支撑 维持动物护理和使用计划需要支持UTEP的强大和产品必不可少的 生物医学研究计划。 1