Identifying mechanisms between hearing loss and falls

识别听力损失和跌倒之间的机制

• 批准号: 10733757
• 负责人: Kristal Mills Riska
• 金额: $ 66.89万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-01 至 2028-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10733757
• 关键词: Accidents; Address; Area; Audiology; Auditory; Awareness; Caring; Case/Control Studies; Cessation of life; Cognitive; Communities; Cues; Diagnosis; Dose; Elderly; Enrollment; Equation; Equilibrium; Event; Fall prevention; Fatigue; Functional disorder; Gait; Goals; Health; Healthcare; Hearing; Hearing Aids; High Prevalence; Individual; Intervention; Link; Measures; Mediating; Modeling; Morbidity - disease rate; Musculoskeletal Equilibrium; National Institute on Deafness and Other Communication Disorders; Otolaryngology; Outcome Study; Participant; Pathway interactions; Patients; Perception; Performance; Peripheral; Physiological; Prevalence; Prevention program; Psychosocial Factor; Public Health; Questionnaires; Rehabilitation therapy; Research; Research Design; Risk Factors; Rotation; Safety; Sampling; Vestibular loss; Work; age related; care burden; cost; disability; fall risk; falls; hearing impairment; hearing loss treatment; improved; innovation; mortality; novel; patient population; programs; prospective; psychosocial; public health relevance; rehabilitation strategy; response; targeted treatment; treatment strategy; vestibular reflex

ABSTRACT Falls result in substantial morbidity, mortality, and disability among older adults. Recently, hearing loss and hearing handicap have been identified as independent risk factors for falls. It is unclear the factors that mediate the association between hearing loss and falls. The long-term goal is to to develop novel interventions that will modify falls risk in the hearing impaired patient population. The current objective is to identify and understand the auditory and vestibular related factors that explain the association between falls and hearing loss and to characterize performance on these candidate factors. To that end, our proposal aims to examine the vestibular- related factors, centrally mediated auditory factors (spatial hearing and listening effort), cognitive, and psychosocial factors in an older adult patient population of fallers and non-fallers. The current proposal is innovative as the work will characterize the extent to which key theoretical factors explain the link between falls and hearing loss and specifically the extent to which unrecognized vestibular dysfunction may explain the association. These contributions will be significant, as they will inform strategies to implement targeted rehabilitation programs to reduce falls and falls-risk in this patient population.

摘要 在老年人中，跌倒会导致严重的发病率、死亡率和残疾。最近，听力损失和 听力障碍已被确定为跌倒的独立危险因素。目前还不清楚调解的因素 听力损失和跌倒之间的联系。长期目标是开发新的干预措施， MODIFY在听力受损患者群体中的跌倒风险。当前的目标是识别和理解 解释跌倒和听力损失之间关系的听觉和前庭相关因素 描述在这些候选因素上的表现。为此，我们的建议旨在检查前庭- 相关因素，中央调节的听觉因素(空间听力和听力努力)，认知，和 失败者和非失败者老年患者群体中的心理社会因素。目前的建议是 尽管这项工作具有创新性，但它将描述关键理论因素解释瀑布之间联系的程度 和听力损失，特别是未识别的前庭功能障碍的程度可以解释 协会。这些贡献将是重大的，因为它们将为实施有针对性的战略提供指导。 康复计划，以减少跌倒和跌倒的风险在这一患者群体。