Psychoeducation for HCV and Alcohol Behaviors

HCV 和酒精行为的心理教育

• 批准号: 7498999
• 负责人: CAROL S NORTH
• 金额: $ 68.24万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7498999
• 关键词: Adherence; Adverse effects; Behavior; Caring; Chronic Disease; Control Groups; Daily; Disease; Drug usage; Education; Educational Curriculum; Educational Intervention; Effectiveness of Interventions; Eligibility Determination; Event; Family; Family Characteristics; Family member; Goals; Health Professional; Hepatitis C; Hepatitis C virus; Housing; Individual; Insurance; Interest Group; Interferons; Intervention; Knowledge; Life; Longevity; Measures; Mediating; Medical; Mental Health; Mental disorders; Modeling; Morbidity - disease rate; Motivation; Outcome; Outcome Measure; Participant; Patients; Pattern; Personality; Pharmaceutical Preparations; Population; Problem Solving; Procedures; Process; Provider; Psychiatric therapeutic procedure; Psychopathology; Quality of life; Randomized Controlled Trials; Readiness; Recommendation; Research Project Grants; Ribavirin; Risk-Taking; Services; Social Functioning; Social support; Solutions; Special Equipment; Standards of Weights and Measures; Substance Abuse, Other; Symptoms; Testing; Training; Translating; Transportation; Treatment Protocols; Viral Load result; alcohol and other drug; alcohol behavior; base; burden of illness; compliance behavior; coping; cost; depressive symptoms; experience; improved; innovation; member; mortality; programs; psychoeducation; satisfaction; severe mental illness; skills

DESCRIPTION (provided by applicant): Medical treatment of hepatitis C (HCV) requires steadfast adherence to be effective, yet physical and psychiatric side effects induced by current medications (interferon and ribavirin) undermine patient motivation and consistency. Barriers to this population's access to vital services, including transportation and insurance and lack of stable housing, pose further threats to optimal management of HCV. Promotion of adherence and patient support may be enhanced if family members and significant others can be enlisted to join HCV providers in this effort. Psychoeducation programs, demonstrated by this team to be effective for patients and families coping with serious mental illness, can have direct relevance and application to HCV. The proposed project will apply a unique, effective family-responsive psychoeducation program (PERF) for HCV, which has not been previously attempted in this population. HCV-PERF will be compared with a didactic education intervention in a randomized controlled trial with 400 HCV patients. The goal is to demonstrate that the intervention will enlarge the eligibility of some patients for HCV treatment and help sustain others through it. The program will provide HCV education and a forum to discuss problems in daily living and coping with the illness in a supportive, proactive, and problem-focused agenda. The topics and issues covered in the psychoeducation groups will emerge from expressed interests of the group members, generating participant-specific discussions emphasizing and reinforcing personalized solutions to the problems of living with a chronic illness and its difficult treatment regimen. This intervention will build on the skills of HCV and mental health professionals with two professionals, one with HCV treatment expertise and the other a with a mental health background, leading the psychoeducation groups. Study participants will be evaluated with several psychospacial/psychiatric measures including coping, functioning, social support, and quality of life as they contemplate or receive standard medical care for HCV. (This research project will not interfere with usual HCV treatment regimens. The problem-solving oriented psychoeducation program is not a replacement for psychiatric care, and psychiatric referrals will be facilitated when appropriate.) Effectiveness of the intervention will be measured through multiple outcome measures, including medical markers such as viral load. This innovative intervention is inexpensive, requires no special equipment or difficult procedures, and can be exported to diverse HCV treatment settings and implemented without extensive training. HCV-PERF has the potential for major positive impact on the HCV population to save lives, reduce costs, and improve medical outcomes.

描述(申请人提供)：丙型肝炎(丙型肝炎)的医学治疗需要坚定不移的坚持才能有效，但目前的药物(干扰素和利巴韦林)引起的身体和精神副作用破坏了患者的动力和一致性。这些人口获得重要服务的障碍，包括交通和保险，以及缺乏稳定的住房，对丙型肝炎病毒的最佳管理构成了进一步的威胁。如果家庭成员和重要的其他人能够加入到这一努力中来，促进遵医和患者支持可能会得到加强。这个团队证明，心理教育计划对患有严重精神疾病的患者和家庭是有效的，可以直接与丙型肝炎病毒相关并应用于此。拟议的项目将对丙型肝炎病毒应用一种独特的、有效的家庭反应心理教育计划(PERF)，这是以前从未在该人群中尝试过的。在一项对400名丙型肝炎患者进行的随机对照试验中，丙型肝炎病毒-PERF将与教育干预进行比较。其目的是证明，干预将扩大一些患者接受丙型肝炎治疗的资格，并帮助其他患者度过难关。该计划将提供丙型肝炎病毒教育和一个论坛，讨论日常生活中的问题，并以支持性、主动性和专注于问题的议程应对这种疾病。心理教育小组所涵盖的主题和问题将来自小组成员表达的兴趣，产生针对特定参与者的讨论，强调并加强针对患有慢性病的问题及其难以治疗的治疗方案的个性化解决方案。这项干预将建立在丙型肝炎病毒和心理健康专业人员的技能基础上，他们有两名专业人员，一名具有丙型肝炎病毒治疗专业知识，另一名具有心理健康背景，领导心理教育小组。研究参与者将接受几项心理空间/精神病学测量，包括应对、功能、社会支持和生活质量，因为他们正在考虑或接受标准的丙型肝炎医疗护理。(该研究项目不会干扰常规的丙型肝炎病毒治疗方案。以解决问题为导向的心理教育计划不能取代精神科护理，在适当的时候将促进精神科转介。)干预的有效性将通过多种结果衡量标准来衡量，包括病毒载量等医学指标。这种创新的干预措施价格低廉，不需要特殊设备或复杂的程序，可以输出到不同的丙型肝炎治疗环境中，无需广泛的培训即可实施。丙型肝炎病毒PERF有可能对丙型肝炎病毒人群产生重大积极影响，以挽救生命、降低成本和改善医疗结果。