Psychoeducation for HCV and Alcohol Behaviors

HCV 和酒精行为的心理教育

• 批准号: 7631889
• 负责人: CAROL S NORTH
• 金额: $ 3.28万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-30 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7631889
• 关键词: Adherence; Adverse effects; Behavior; Caring; Chronic Disease; Control Groups; Daily; Disease; Drug usage; Education; Educational Curriculum; Educational Intervention; Effectiveness of Interventions; Eligibility Determination; Event; Family; Family Characteristics; Family member; Goals; Health Professional; Hepatitis C; Hepatitis C virus; Housing; Individual; Insurance; Interest Group; Interferons; Intervention; Knowledge; Life; Longevity; Measures; Mediating; Medical; Mental Health; Mental disorders; Modeling; Morbidity - disease rate; Motivation; Outcome; Outcome Measure; Participant; Patients; Pattern; Personality; Pharmaceutical Preparations; Population; Problem Solving; Procedures; Process; Provider; Psychiatric therapeutic procedure; Psychopathology; Quality of life; Randomized Controlled Trials; Readiness; Recommendation; Ribavirin; Risk-Taking; Services; Social Functioning; Social support; Solutions; Special Equipment; Standards of Weights and Measures; Substance Abuse, Other; Symptoms; Testing; Training; Translating; Transportation; Treatment Protocols; Viral Load result; alcohol and other drug; alcohol behavior; base; burden of illness; compliance behavior; coping; cost; depressive symptoms; experience; improved; innovation; member; mortality; programs; psychoeducation; satisfaction; severe mental illness; skills

Medical treatment of hepatitis C (HCV) requires steadfast adherence to be effective, yet physical and psychiatric side effects induced by current medications (interferon and ribavirin) undermine patient motivation and consistency. Barriers to this population's access to vital services, including transportation and insurance and lack of stable housing, pose further threats to optimal management of HCV. Promotion of adherence and patient support may be enhanced if family members and significant others can be enlisted to join HCV providers in this effort. Psychoeducation programs, demonstrated by this team to be effective for patients and families coping with serious mental illness, can have direct relevance and application to HCV. The proposed project will apply a unique, effective family-responsive psychoeducation program (PERF) for HCV, which has not been previously attempted in this population. HCV-PERF will be compared with a didactic education intervention in a randomized controlled trial with 400 HCV patients. The goal is to demonstrate that the intervention will enlarge the eligibility of some patients for HCV treatment and help sustain others through it. The program will provide HCV education and a forum to discuss problems in daily living and coping with the illness in a supportive, proactive, and problem-focused agenda. The topics and issues covered in the psychoeducation groups will emerge from expressed interests of the group members, generating participant-specific discussions emphasizing and reinforcing personalized solutions to the problems of living with a chronic illness and its difficult treatment regimen. This intervention will build on the skills of HCV and mental health professionals with two professionals, one with HCV treatment expertise and the other a with a mental health background, leading the psychoeducation groups. Study participants will be evaluated with several psychospcial/psychiatric measures including coping, functioning, social support, and quality of life as they contemplate or receive standard medical care for HCV. (Thisresearch project will not interfere with usual HCV treatment regimens. The problem-solving oriented psychoeducation program is not a replacement for psychiatric care, and psychiatric referrals will be facilitated when appropriate.) Effectiveness of the intervention will be measured through multiple outcome measures, including medical markers such as viral load. This innovative intervention is inexpensive, requires no special equipment or difficult procedures, and can be exported to diverse HCV treatment settings and implemented without extensive training. HCV-PERFhas the potential for major positiveimpact on the HCV population to save lives, reduce costs, and improve medical outcomes.

丙型肝炎 (HCV) 的药物治疗需要坚持不懈地坚持才能有效，但身体和 当前药物（干扰素和利巴韦林）引起的精神副作用会削弱患者的积极性 和一致性。该人群获得交通和保险等重要服务的障碍 以及缺乏稳定的住房，对 HCV 的最佳管理构成进一步的威胁。促进遵守和 如果可以招募家庭成员和重要其他人加入 HCV，则可能会增强患者支持 提供者在这方面的努力。该团队证明心理教育计划对患者和患者有效 应对严重精神疾病的家庭可能与丙型肝炎病毒有直接的相关性和应用。 拟议的项目将采用独特、有效的家庭响应心理教育计划 （PERF）针对 HCV，以前从未在该人群中尝试过。 HCV-PERF 将进行比较 在一项对 400 名 HCV 患者进行的随机对照试验中进行教学教育干预。目标是 证明干预措施将扩大一些患者接受 HCV 治疗的资格并帮助 通过它支持他人。该计划将提供 HCV 教育和讨论日常问题的论坛 以支持性、主动性和以问题为中心的议程生活和应对疾病。主题和 心理教育小组涵盖的问题将源于小组成员表达的兴趣， 产生针对特定参与者的讨论，强调和加强针对问题的个性化解决方案 患有慢性疾病的问题及其困难的治疗方案。这项干预措施将建立在 HCV 和心理健康专业人员的技能，其中包括两名专业人员，其中一名具有 HCV 治疗专业知识 另一名具有心理健康背景，领导心理教育小组。研究参与者 将通过多种心理/精神措施进行评估，包括应对、功能、社交 他们考虑或接受 HCV 标准医疗护理时的支持和生活质量。 （本研究 项目不会干扰通常的丙肝治疗方案。以解决问题为导向 心理教育计划不能替代精神科护理，精神科转诊将是 适当时促进。）干预的有效性将通过多种结果来衡量 措施，包括病毒载量等医学标记。这种创新的干预措施成本低廉， 不需要特殊设备或困难的程序，可输出到多种HCV治疗 设置和实施无需大量培训。 HCV-PERF 具有产生重大积极影响的潜力 旨在拯救 HCV 人群的生命、降低成本并改善医疗结果。