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Granulocyte Colony Stimulating Factor Treatment For Croh

Granulocyte Colony Stimulating Factor Treatment For Croh
粒细胞集落刺激因子治疗克罗氏病
批准号：
6822102
负责人：
Peter Mannon
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/6822102
关键词：
Crohn's disease cellular immunity clinical research colony stimulating factor cytokine dendritic cells endoscopy enzyme linked immunosorbent assay flow cytometry gastrointestinal disorder chemotherapy gastrointestinal imaging /visualization gastrointestinal pharmacology helper T lymphocyte human subject human therapy evaluation inflammatory bowel diseases lymphocyte patient oriented research polymerase chain reaction tissue /cell culture

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中文摘要
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英文摘要
This open-label trial of G-CSF in Crohn's disease seeks to establish the safety and study the efficacy of this drug to induce remission in moderately active disease. We have screened 10 and enrolled 9 subjects in this protocol to date. Responses have ranged from complete remission to no response at all. We are accruing data on changes in cytokine secretion by peripheral and lamina propria mononuclear cells and dendritic cell populations. We are correlating these with clinical parameters including biochemical markers of gut inflammation.
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The Role of Microbial Antigen-Specific T Cells in Crohn's disease
  • 批准号：
    10615271
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2018
  • 负责人：
    Peter Mannon
  • 依托单位：
    OMAHA VA MEDICAL CENTER
The Role of Microbial Antigen-Specific T Cells in Crohn's disease
  • 批准号：
    10683732
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2018
  • 负责人：
    Peter Mannon
  • 依托单位：
    OMAHA VA MEDICAL CENTER
The Role of Microbial Antigen-Specific T Cells in Crohn's disease
  • 批准号：
    10617869
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2018
  • 负责人：
    Peter Mannon
  • 依托单位：
    OMAHA VA MEDICAL CENTER
The Role of Microbial Antigen-Specific T Cells in Crohn's disease
  • 批准号：
    10307987
  • 项目类别：
  • 资助金额：
    $0.0万
  • 财政年份：
    2018
  • 负责人：
    Peter Mannon
  • 依托单位：
    BIRMINGHAM VA MEDICAL CENTER
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