Formative Research on Latinos and Leaders on HPV Vaccine Acceptance and Promotion

拉丁裔和领导者对 HPV 疫苗接受和推广的形成性研究

• 批准号: 7458231
• 负责人: PAULA A ESPINOZA
• 金额: $ 7.7万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-05-06 至 2010-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7458231
• 关键词: 18 year old; Advisory Committees; Attitude; Awareness; Behavior; Belief; Clinical Trials; Communities; Confusion; Depth; Development; Diagnostic tests; Doctor of Philosophy; Effectiveness; Emotional; Evaluation; Face; Female Adolescents; Focus Groups; Goals; Human Papilloma Virus Vaccine; Human Papillomavirus; Human papilloma virus infection; Incidence; Infection; Intervention; Interview; Knowledge; Latina; Latino; Link; Malignant Neoplasms; Methods; National Cancer Institute; Outcome Study; Parents; Phase; Pilot Projects; Provider; Research; Research Personnel; Research Proposals; Risk; Services; Social Marketing; Testing; Vaccines; Work; behavior change; community based participatory research; cost; design; follow-up; girls; mortality; programs; tool; transmission process

DESCRIPTION (provided by applicant): This pilot project proposes formative work by a team of long-standing collaborators on Latina cancer issues. It will focus on developing culturally relevant social marketing tools to promote Human Papillomavirus (HPV) vaccine to increase acceptance of the vaccine among parents of Latina girls from 9 to 18 years old. Tools that will promote increase are highly needed given that during the clinical trial phase of the HPV vaccine, barriers to large-scale acceptance of HPV vaccines were identified. A 2005 review article describes the challenges facing HPV vaccine promotion: a) the public's lack of knowledge and understanding of HPV; b) confusion over high-risk strains; c) lack of understanding about infection sequaelae and link to cancers; d) lack of knowledge regarding the transmission of HPV; and b) providers' discomfort in discussing HPV. Formative evaluation methods will be implemented among Latino parents and opinion and community leaders. Up to 60 Latino parents will participate in 6 focus groups and 10 community leaders will be interviewed in key informant interviews. The outcome of this study is the design of social marketing interventions that will stimulate acceptance of the HPV vaccine among the parents of Latino adolescent girls. Social Marketing is the approach employed in this pilot since it focuses on behavior change rather than simply increasing awareness and knowledge. Social Marketing is consistent with the goals of community- based participatory research (CBPR) by emphasizing community involvement at all levels of research, and the involvement of those who will be impacted and benefited by the interventions. Through a partnership approach, this proposal seeks to gain commitment and support for HPV vaccine interventions such as those found in other CBPR efforts. This proposal intends to develop interventions that will reduce the disproportionate burden Latinas face with respect to cancer incidence and mortality and decrease the cost and emotional burden of diagnostic tests and services as a result of HPV infection. Pursuant to this goal, four specific aims will be attained as discussed below. Specific Aim 1: Conduct focus groups of Latino parents of adolescent girls to explore their knowledge, attitudes, beliefs and behaviors related to the HPV vaccine, and potential intervention strategies to inform the development of a social marketing plan to promote HPV vaccine among Latinas. Specific Aim 2: Formulate a social marketing plan and intervention to promote HPV vaccine utilization to be reviewed through key informant interviews and advisory committee. Specific Aim 3: Conduct in-depth interviews of key informant opinion leaders regarding the feasibility, appropriateness, effectiveness and sustainability of the social marketing plan to promote HPV vaccine use among Latinas. Specific Aim 4: Prepare and submit a follow-up R21 research proposal to the National Cancer Institute to pilot test the proposed HPV vaccine intervention.

描述(由申请者提供)：这个试点项目建议由一个长期的合作者团队在拉丁裔癌症问题上进行形成性工作。它将专注于开发与文化相关的社会营销工具，以推广人乳头状瘤病毒(HPV)疫苗，以提高9至18岁拉丁裔女孩的父母对该疫苗的接受度。鉴于在HPV疫苗的临床试验阶段，已经确定了大规模接受HPV疫苗的障碍，因此迫切需要促进增加的工具。2005年的一篇综述文章描述了推广HPV疫苗所面临的挑战：a)公众对HPV缺乏了解和了解；b)对高危毒株感到困惑；c)对感染后遗症和与癌症的联系缺乏了解；d)缺乏关于HPV传播的知识；以及b)提供者在讨论HPV时感到不适。将在拉丁裔家长、舆论和社区领袖中实施形成性评估方法。多达60名拉丁裔家长将参加6个焦点小组，10名社区领导人将在关键线人访谈中接受采访。这项研究的结果是设计了社会营销干预措施，将促进拉丁裔青春期女孩的父母接受HPV疫苗。社会营销是这个试点中采用的方法，因为它关注的是行为的改变，而不是简单地增加意识和知识。社会营销与以社区为基础的参与性研究(CBPR)的目标一致，强调社区在所有研究层面的参与，以及那些将受到影响并从干预措施中受益的人的参与。通过伙伴关系方法，该提案寻求获得对HPV疫苗干预措施的承诺和支持，例如在其他CBPR努力中发现的干预措施。这项提议旨在制定干预措施，以减轻拉丁美洲人在癌症发病率和死亡率方面面临的不成比例的负担，并减少由于HPV感染而导致的诊断测试和服务的费用和情感负担。根据这一目标，将实现下面讨论的四个具体目标。具体目标1：对青春期女孩的拉丁裔父母进行重点小组调查，探讨他们与HPV疫苗有关的知识、态度、信念和行为，以及潜在的干预战略，以便为在拉丁裔中推广HPV疫苗的社会营销计划的制定提供信息。具体目标2：制定促进HPV疫苗使用的社会营销计划和干预措施，并通过关键线人访谈和咨询委员会进行审查。具体目标3：就促进拉丁裔人使用HPV疫苗的社会营销计划的可行性、适当性、有效性和可持续性，对主要的信息提供人的意见领袖进行深入访谈。具体目标4：准备并向国家癌症研究所提交后续的R21研究提案，以试点测试拟议的HPV疫苗干预。