Automated enhancement and correction of brain MRI images that leverages the entire imaging exam

利用整个成像检查自动增强和校正脑部 MRI 图像

• 批准号: 10760852
• 负责人: ZeChen Zhou
• 金额: $ 30万
• 依托单位: SUBTLE MEDICAL, INC.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-05 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10760852
• 关键词: Abbreviations; Acceleration; Age; Brain; Brain imaging; Cohort Studies; Collaborations; Computer software; Diagnostic; Equipment; Frequencies; Growth; Health system; Image; Imaging Device; Magnetic Resonance Imaging; Medical; Modeling; Morphologic artifacts; Motion; Output; Patient Care; Phase; Population; Protocols documentation; Quality of Care; Radiology Specialty; Reporting; Scanning; Services; Specialist; System; Time; United States; Universities; Washington; brain magnetic resonance imaging; contrast imaging; deep learning; deep learning model; denoising; diagnostic value; experience; forgetting; imaging facilities; imaging study; improved; machine learning method; medical specialties; operation; radiologist; tool; trend; ultra high resolution

Project Summary/Abstract Subtle Medical, Inc. (Subtle), in collaboration with the University of Washington, proposes a Fast-Track project to develop and validate a software product capable of enhancing an entire brain magnetic resonance imaging (MRI) study. The proposed system will use state-of-the-art machine learning methods to build a product that integrates seamlessly into the Radiology workflow and standard patient care path to determine if any required MRI acquisitions are missing or corrupted, then correct the corrupted acquisitions and synthesize the missing acquisitions by incorporating the information contained in the appropriately acquired acquisitions. Brain studies make up approximately 20% of all MRI studies worldwide, and nearly all brain studies acquire multiple image contrasts to obtain complementary information. It has been reported that nearly 60% of all MRI acquisitions contain at least minimal motion artifacts. Moreover, important acquisitions are frequently skipped or forgotten during the study. The result is that a significant fraction of brain MRI studies are sent to radiologists with missing or poor-quality exam sequences that can reduce the quality of care while increasing the burden on the radiologist to read a suboptimal study. A successful completion of this project will result in a tool for imaging centers that will improve the consistency and quality of brain MRI studies and allow them to increase their throughput by removing the need to rescan acquisitions with artifacts. This will improve the experience and care of the patients while reducing the burden on radiologists and improving the efficiency of the imaging center’s operations.

项目摘要/摘要 微妙医疗公司与华盛顿大学合作，提出了一个快速通道项目 开发和验证能够增强整个大脑磁共振成像的软件产品 (MRI)研究。拟议的系统将使用最先进的机器学习方法来构建一种产品 无缝集成到放射工作flOW和标准患者护理路径中，以确定是否有 所需的MRI采集丢失或损坏，然后更正损坏的采集并合成 通过合并适当收购的收购中包含的信息而错过收购。 大脑研究约占全球所有核磁共振研究的20%，几乎所有的大脑研究都获得了 通过多幅图像的对比度来获取互补信息。据报道，近60%的所有 磁共振成像采集至少包含最小的运动伪影。此外，重要的收购往往是 在学习过程中跳过或忘记。结果是，很大一部分脑部核磁共振研究被发送到fi 放射科医生的检查序列缺失或质量不佳，可能会降低护理质量，同时增加 放射科医生阅读一份不太理想的研究报告的负担。这个项目的成功完成将导致 一种用于成像中心的工具，将提高脑MRI研究的一致性和质量，并允许 通过消除重新扫描具有人工制品的采集的需要来增加其吞吐量。这将改善 在减轻放射科医生负担提高工作效率的同时体验和护理患者 影像中心的运作。