Automated enhancement and correction of brain MRI images that leverages the entire imaging exam

项目总结/摘要 Subtle Medical，Inc.（Subtle）与华盛顿大学合作，提出了一个快速通道项目 开发和验证能够增强整个大脑磁共振成像的软件产品， (MRI)study.拟议中的系统将使用最先进的机器学习方法来构建一个产品， 无缝集成到放射科工作流程和标准患者护理路径中，以确定是否存在 所需的MRI采集丢失或损坏，然后纠正损坏的采集并合成 通过纳入适当获取的收购中包含的信息来弥补遗漏。 脑部研究约占全球所有MRI研究的20%，并且几乎所有脑部研究都获得了 多个图像对比以获得互补信息。据报道，近60%的 MRI采集至少包含最小的运动伪影。此外，重要的收购往往 在学习过程中被忽略或遗忘。结果是，很大一部分脑部MRI研究被发送到 放射科医生缺少或质量差的检查序列，这可能会降低护理质量，同时增加 放射科医生阅读次优研究的负担。该项目的成功完成将导致 这是一个成像中心的工具，将提高大脑MRI研究的一致性和质量，并允许他们 以通过消除重新扫描具有伪影的采集的需要来增加其吞吐量。这将改善 在减轻放射科医生负担和提高放射科医生效率的同时， 影像中心的运作

Project Summary/Abstract Subtle Medical, Inc. (Subtle), in collaboration with the University of Washington, proposes a Fast-Track project to develop and validate a software product capable of enhancing an entire brain magnetic resonance imaging (MRI) study. The proposed system will use state-of-the-art machine learning methods to build a product that integrates seamlessly into the Radiology workflow and standard patient care path to determine if any required MRI acquisitions are missing or corrupted, then correct the corrupted acquisitions and synthesize the missing acquisitions by incorporating the information contained in the appropriately acquired acquisitions. Brain studies make up approximately 20% of all MRI studies worldwide, and nearly all brain studies acquire multiple image contrasts to obtain complementary information. It has been reported that nearly 60% of all MRI acquisitions contain at least minimal motion artifacts. Moreover, important acquisitions are frequently skipped or forgotten during the study. The result is that a significant fraction of brain MRI studies are sent to radiologists with missing or poor-quality exam sequences that can reduce the quality of care while increasing the burden on the radiologist to read a suboptimal study. A successful completion of this project will result in a tool for imaging centers that will improve the consistency and quality of brain MRI studies and allow them to increase their throughput by removing the need to rescan acquisitions with artifacts. This will improve the experience and care of the patients while reducing the burden on radiologists and improving the efficiency of the imaging center’s operations.