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A Self-Guided Mobile Intervention for Adults with Binge Eating and Obesity

针对成人暴饮暴食和肥胖症的自助式移动干预

基本信息

批准号：
10761112
负责人：
Seth Feuerstein
金额：
$ 37.53万
依托单位：
OUI THERAPEUTICS, INC
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-09-01 至 2024-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10761112
关键词：
Accountability Address Adult Age American Behavior Therapy Behavioral Binge Eating Body Weight decreased Body mass index Budgets Clinical Clinical Trials Cognitive Therapy Cost Savings Country Data Eating Eating Behavior Eating Disorders Esthetics Evidence based treatment Food Goals Health Health Care Costs Healthcare Individual Infrastructure Intervention Interview Knowledge Letters Marketing Modality Obesity Outcome Patient Recruitments Phase Prevalence Provider Questionnaires Recurrence Research Personnel Site Testing Therapeutic Time Training Weight Work adaptive intervention adult obesity arm chatbot commercialization comorbidity cost cost estimate design design,build,test digital digital delivery digital health digital intervention digital treatment experience follow-up improved mobile application novel obesity treatment open label peer personalized intervention pharmacy benefit post intervention programs retention rate tool usability weight loss intervention

项目摘要

ABSTRACT Obesity and comorbid binge eating are serious health problems for more than 40% of adults across the US.7 Health complications due to obesity comprise more than 20% of the nation’s healthcare budget, and the healthcare costs of individuals with binge eating are $18,152 higher than in obese peers without binge eating.13 The prevalence of binge eating and the substantial burden of healthcare costs highlight the need for treatments that eliminate binge eating and produce weight loss. Despite this, there is a paucity of interventions that address these comorbid conditions. In this Phase 1 project, we seek to build a digital therapeutic (called OTX-401) that will be ready for testing in a large, multi-site, well-powered clinical trial during Phase 2. Positive results will be the critical initial step to facilitating the widespread implementation and commercialization of the digital therapeutic to enhance access to highly personalized obesity and binge eating intervention.

摘要肥胖和共病暴食是美国40%以上成年人的严重健康问题。肥胖引起的健康并发症占国家医疗预算的20%以上，暴饮暴食者的医疗保健费用比没有暴饮暴食的肥胖同龄人高出18，152美元。暴饮暴食的流行和医疗费用的巨大负担突出了治疗的必要性消除暴饮暴食并减轻体重。尽管如此，仍然缺乏干预措施，解决这些并发症。在这个第一阶段的项目中，我们寻求建立一个数字治疗（称为 OTX-401），将准备在第2阶段进行大型、多中心、动力良好的临床试验。积极结果将是促进广泛实施和商业化的关键的第一步，数字治疗，以提高获得高度个性化的肥胖和暴饮暴食干预。