Rocky Mountain REACH (RMT-REACH)

落基山 REACH (RMT-REACH)

• 批准号: 10783596
• 负责人: Karen Brown
• 金额: $ 100万
• 依托单位: UNIVERSITY OF MONTANA
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-09-25 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10783596
• 关键词: Academia; Academic support; Acceleration; Address; Alaska; Area; Biological Sciences; Biomedical Research; Businesses; Clinical; Collaborations; Communities; Development; Devices; Diagnostic; Economic Development; Ecosystem; Ensure; Entrepreneurship; Equity; Evaluation Research; Fostering; Funding; Geography; Goals; Growth; Health; Health Personnel; Health system; Human; Idaho; Industry; Infrastructure; Institution; Investments; Leadership; Legal; Life Cycle Stages; Location; Marketing; Medical; Medical Device; Mentors; Minority; Modeling; Montana; Pathway interactions; Persons; Pharmaceutical Preparations; Positioning Attribute; Recording of previous events; Research; Research Personnel; Resource Allocation; Resource-limited setting; Resources; Rural; Rural Community; System; Technology; Therapeutic; Training; Translations; Tribes; United States; United States National Institutes of Health; Universities; Washington; Woman; Wyoming; burden of illness; college; commercialization; community college; design; experience; health disparity; health disparity populations; innovation; medically underserved population; metropolitan; mortality; next generation; novel diagnostics; product development; programs; prototype; research and development; success; technical college; tribal college; tribal community; tribal institution; undergraduate student; underserved community

PROJECT SUMMARY/ABSTRACT The L.S. Skaggs Institute for Health Innovation (SIHI)-Research Evaluation and Commercialization Hub (SIHI- REACH) at the University of Montana (UM) will catalyze the emerging biomedical industry corridor in Montana and the surrounding states by establishing a hub to accelerate translation of academic discoveries into products that impact human health. Untapped opportunities exist in IDeA states to turn biomedical research discoveries into technologies that address unmet medical needs, disease burden, and health disparities for populations across the United States (US). We have partnered with 10 academic institutions across the IDeA states in the Washington, Wyoming, Alaska, Montana, and Idaho (WWAMI) region—including a community, a technological, and a tribal college—as well as the Washington Entrepreneurial-REACH (WE-REACH) at the University of Washington to gain invaluable guidance from their leadership team. Academic discovery is indispensable for ensuring a pipeline of research for novel diagnostics, devices, and therapies, yet sustainable infrastructure to support academic innovators in resource-limited regions has yet to be fully realized. Geographically remote regions have unique challenges in developing and promoting commercialization and entrepreneurship, including lack of infrastructure, less access to innovators and subject matters experts, and lower levels of funding. Gaps in resource allocation contribute to higher rates of mortality and disease burden, and health systems in these areas have traditionally been late to implement health innovation when compared to their metropolitan counterparts. In order for health innovation to reach clinical usefulness for all people, efforts are needed to ensure the inclusion of minority, geographically-isolated, and historically medically underserved populations at every stage of the biomedical research life cycle. We will accomplish our ultimate goals through the following aims: 1) Identify emerging biomedical discoveries with commercial viability in academic institutions within the four regional IDeA states supported by SIHI-REACH, emphasizing discoveries that address disease burden and health disparities for underserved communities; 2) Develop an innovative implementation system to enable access to gap funding, key subject matter experts in areas of product development, regulatory, reimbursement, legal, business development, and overall commercial strategy for academic researchers in resource-limited areas; 3) Provide funding and project management support for promising technologies and development teams to accelerate product definition studies; and 4) Elevate a WWAMI region-wide pro-entrepreneurial culture among academic investigators by engaging and mentoring biomedical innovators in rural and tribal institutions. With a strong leadership team providing diverse and complementary expertise and proven experience in entrepreneurial startups, SIHI-REACH will train the next generation of biomedical innovators in entrepreneurship and product development, positively impact the regional economy, and bring products that address health disparities to market. 1

项目摘要/摘要 L.S. Skaggs健康创新研究所（SIHI） - 研究评估与商业化中心（Sihi- 蒙大拿大学（UM）的覆盖范围）将催化蒙大拿州新兴的生物医学行业走廊 以及周围的国家通过建立一个枢纽，将学术发现的翻译转化为 影响人类健康的产品。思想状态中存在未开发的机会来转向生物医学研究 发现未满足医疗需求，疾病伯恩和健康分布的技术 美国（美国）的人口。我们已经与10个学术机构合作 华盛顿，怀俄明州，阿拉斯加，蒙大拿州和爱达荷州（第二次世界大战）地区的国家 - 包括一个社区，一个 技术和一所部落学院 - 以及华盛顿的企业家范围（WE-REACH） 华盛顿大学获得领导团队的宝贵指导。学术发现是 必不可少的方法是确保用于新型诊断，设备和疗法的研究渠道，但可持续 支持资源有限地区的学术创新者的基础设施尚未完全实现。 地理上偏远地区在开发和促进商业化方面面临着独特的挑战 企业家精神，包括缺乏基础设施，更少的创新者和主题专家的访问权限以及 较低的资金水平。资源分配的差距有助于较高的死亡率和疾病伯恩（Burnen）， 传统上，这些领域的卫生系统比较实施健康创新 与他们的大都市同行。为了使健康创新达到所有人的临床实用性， 需要努力以确保包括少数民族，地理上隔离和历史上的少数民族 在生物医学研究生命周期的每个阶段，服务不足的人群。我们将完成我们的最终 通过以下目的实现目标：1）以商业生存能力确定新兴的生物医学发现 Sihi-reach支持的四个区域思想国家中的学术机构，强调发现 解决伯恩疾病的疾病和服务不足的社区的健康分配； 2）发展创新 实施系统以启用差距资金，产品领域的关键主题专家 开发，监管，报销，法律，业务发展和整体商业策略 资源有限领域的学术研究人员； 3）提供资金和项目管理支持 有希望的技术和开发团队加速产品定义研究； 4）提升 通过参与和心理的学术研究者之间的WWAMI地区范围内的企业家文化 农村和部落机构的生物医学创新者。有一个强大的领导团队提供潜水员和 Sihi-Reach将在创业初创公司中完全专业知识和经验丰富的经验，将在下一个训练 产生企业家和产品开发领域的生物医学创新者，对 区域经济，并将针对健康分配的产品带入市场。 1