FETAL ANDROGEN EXCESS AND POLYCYSTIC OVARIAN SYNDROME

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: The Northwestern University Specialized Center of Research (SCOR) on Sex and Gender Factors Affecting Women's Health is a multidisciplinary NIH-funded program and includes investigators from two National Primate Research Centers, Pennsylvania State University, the University of Chicago, and the Mayo Clinic. Overall, projects are focused on the etiology of polycystic ovary syndrome, and include specific aims to determine the gene region associated with this syndrome, and how such genes result in reproductive abnormalities and an increased risk for diabetes. This SCOR encompasses human and nonhuman primate studies, and uses the monkey model to explore the syndrome proposed to be associated with prenatal androgen excess.