FETAL ANDROGEN EXCESS AND POLYCYSTIC OVARIAN SYNDROME

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 目的：西北大学性别和性别因素影响女性健康的专门研究中心(SCOR)是由美国国立卫生研究院资助的一个多学科项目，包括来自宾夕法尼亚州立大学、芝加哥大学和梅奥诊所两个国家灵长类研究中心的研究人员。总体而言，项目的重点是多囊卵巢综合征的病因学，包括确定与该综合征相关的基因区域，以及这些基因如何导致生殖异常和糖尿病风险增加。这项SCOR包括人类和非人类灵长类动物的研究，并使用猴子模型来探索被认为与产前雄激素过量有关的综合征。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: The Northwestern University Specialized Center of Research (SCOR) on Sex and Gender Factors Affecting Women's Health is a multidisciplinary NIH-funded program and includes investigators from two National Primate Research Centers, Pennsylvania State University, the University of Chicago, and the Mayo Clinic. Overall, projects are focused on the etiology of polycystic ovary syndrome, and include specific aims to determine the gene region associated with this syndrome, and how such genes result in reproductive abnormalities and an increased risk for diabetes. This SCOR encompasses human and nonhuman primate studies, and uses the monkey model to explore the syndrome proposed to be associated with prenatal androgen excess.