FETAL ANDROGEN EXCESS AND POLYCYSTIC OVARIAN SYNDROME

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 目的：西北大学关于影响妇女健康的性和性别因素的专门研究中心（SCOR）是一个多学科的NIH资助的项目，包括来自两个国家灵长类动物研究中心、宾夕法尼亚州立大学、芝加哥大学和马约诊所的研究人员。 总体而言，项目的重点是多囊卵巢综合征的病因，包括确定与该综合征相关的基因区域的具体目标，以及这些基因如何导致生殖异常和糖尿病风险增加。该SCOR包括人类和非人类灵长类动物研究，并使用猴模型来探索与产前雄激素过多相关的综合征。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Objective: The Northwestern University Specialized Center of Research (SCOR) on Sex and Gender Factors Affecting Women's Health is a multidisciplinary NIH-funded program and includes investigators from two National Primate Research Centers, Pennsylvania State University, the University of Chicago, and the Mayo Clinic. Overall, projects are focused on the etiology of polycystic ovary syndrome, and include specific aims to determine the gene region associated with this syndrome, and how such genes result in reproductive abnormalities and an increased risk for diabetes. This SCOR encompasses human and nonhuman primate studies, and uses the monkey model to explore the syndrome proposed to be associated with prenatal androgen excess.