Pilot/Feasibility Studies Program of the HCV Persistence Study Group (HPSG)

PFS的总体目标是鼓励与病毒持续机制相关的创新研究。 这项计划是一个机制，通过这个合作学习小组将促进 年轻的研究人员专注于与HPSG的科学任务相关的领域，并将鼓励 调查人员将他们的研究扩展到慢性病毒感染，通常与世界卫生组织的成员合作 HPSG直接关注这些障碍。一个重要的并行目标是促进青少年的成长 调查人员，希望增加研究这些疾病的工作人员的数量。应该是 强调PFS奖励的目的不是作为调查人员“在拨款之间”的“过渡性资助” 或支持尚未得到外部资助机构支持的项目。预计PFS收件人 将导致由外部同行审查机构提供进一步的、持续的研究资金，以及有保证的结果 在同行评议的期刊上发表。我们会考虑资助三类一般类型的私营机构资助计划： I型来自年轻研究人员，目前或过去没有独立的NIH支持建立 与HPSG目标相关的研究计划。这类奖项的申请者 一般持有最初的教职；高级博士后研究员也可以申请，如果有 是他们系的书面承诺，还是PFS内的教员任命？ 支持期 II型来自知名科学家，目前没有关注新出现的慢性感染 病原体本身，他们将扩展他们的研究，以涵盖直接或间接的问题 认识慢性病毒感染的重要性 第三类来自研究人员，他们的新项目明显从他们已有的研究中剔除 程序。 所有参与HPSG机构的成员都有资格通过PFS计划获得资金。 他们将参加HPSG研讨会，与其他中心调查人员互动，并展示他们的发现 除向执行委员会提交下文所述的正式报告外，还应向高级别特设工作组成员提交报告。 虽然PFS方案的目标包括上述三种类型的应用，但第一类 提案具有最高的优先级。在HPSG期间，调查员不得获得一次以上的PFS奖 授权期。

The overall goal of the PFS is to stimulate innovative research relevant to mechanisms of viral persistence. This program is one mechanism through which this collaborative Study Group will facilitate the development of young investigators focused on areas relevant to the scientific mission of the HPSG and will encourage basic investigators to extend their studies into chronic viral infections, often in collaboration with members of the HPSG directly focused on these disorders. An important parallel goal is to foster the growth of young investigators, in the hope of increasing the number of workers studying these disorders. It should be emphasized that PFS awards are not designed to serve as "bridge funding" for investigators "between grants" or to support projects with pending support from outside funding agencies. It is anticipated that PFS recipients will lead to further, ongoing research funding by external peer-reviewed agencies as well as results warranting publication in peer-reviewed journals. Three general types of PFS applications will be considered for funding: TYPE I Those from young investigators without current or past independent NIH support establishing research programs relevant to the Aims of the HPSG. Applicants for this type of award generally hold an initial faculty appointment; senior post-doctoral fellows may also apply if there is a documented commitment by their department t a faculty appointment within the PFS support period TYPE II Those from established scientists not currently focused on chronic infection with Emerging Pathogens per se who will extend their studies to encompass issues of direct of indirect importance to understanding chronic viral infection TYPE III Those from investigators with novel projects distinctly removed from their established research program. All members of the participant HPSG institutions are eligible to receive funding through the PFS program. They are expected to attend HPSG seminars, interact with other center investigators and present their findings to the members of the HPSG in addition to formal reporting to the Executive Committee as described below. While the goals of the PFS program encompasses the three types of applications noted above, TYPE I proposals have highest priority. An investigator may not receive more than one PFS award during the HPSG grant period.