Diagnostics

诊断

• 批准号: 7678801
• 负责人: RICHARD E ROTHMAN
• 金额: $ 36.31万
• 依托单位: UNIVERSITY OF MARYLAND BALTIMORE
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-03-01 至 2009-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7678801
• 关键词: Accident and Emergency department; Acute; Animals; Area; Biological Assay; Caring; Centers for Disease Control and Prevention (U.S.); Clinical; Detection; Development; Diagnosis; Diagnostic; Diagnostic Reagent; Doctor of Philosophy; Drug resistance; Emergency Medicine; Ensure; Epidemic; Event; Fellowship; Fingerprint; Goals; Human; Industry; Infectious Agent; Interdisciplinary Study; Invasive; Laboratories; Lead; Measures; Molecular; Molecular and Cellular Biology; Mutation; Patients; Performance; Polymerase Chain Reaction; Primates; Principal Investigator; Program Development; Proteomics; Qualifying; Reproducibility; Research; Sampling; Sensitivity and Specificity; Specimen; Surveillance Methods; System; Training; Translational Research; Universities; Validation; Viral; Wages; Work; biothreat; communicable disease diagnosis; design; experience; innovation; medical schools; microbial; pathogen; professor; programs; rapid detection; response; validation studies

PROJECT 3. DEVELOPMENT OF RAPID INNOVATIVE DIAGNOSTIC PLATFORMS FOR ROUTINE CLINICAL USE IN KNOWN OR SUSPECTED BT EVENTS (ROTHMAN) Richard Rothman MD, PhD, Principal Investigator for the Diagnostics Project, is an Assistant Professor in the Department of Emergency Medicine, Johns Hopkins University School of Medicine. Dr. Rothman developed his current translational research program through doctoral training in cellular and molecular biology at UCSF, course work and experience during his research fellowship training, and subsequent multidisciplinary collaborations both internal and external to Johns Hopkins University. His work focuses on basic molecular innovations (such as polymerase chain reaction) for rapid detection of biologic agents in acute care settings. The ability to bridge both clinical, laboratory, and epidemiological surveillance methods makes him uniquely qualified to lead this program for the development of biotech detection systems. Dr. Rothman is the Research Fellowship Director in the Department of Emergency Medicine and serves as a consultant both for the biotech industry in the BT arena, and for the Centers for Disease Control and Prevention in the area of acute diagnosis of infectious diseases. Dr. Rothman will provide overall direction and coordination for the Diagnostics Project, ensuring that the overall goals and objectives are met. He will coordinate the various sub-projects and provide guidance as to appropriateness of assays for clinical use. He will act as liaison between the primate center and other RCE projects for sharing of diagnostic assay platforms, diagnostic reagents, and clinical human and animal specimens as a means of furthering the goals of not only the Diagnostic Project, but those of the other RCE projects. 10% salary support is requested.

项目3。快速创新诊断平台的开发