Problem Solving in Transplant Patients and Caregivers

本研究的目的是测试潜在的应用解决问题的教育干预的患者和家庭照顾者经历异基因造血干细胞移植（HSCT）。增加解决问题的能力可以减少痛苦，并可能改善症状和健康相关的QOL。准备好的家庭护理干预，也被称为科普，已证明对癌症患者及其家庭有益，但其目前的应用存在局限性。只有一项研究报告了这种干预在急性护理环境中的应用，没有对接受HSCT的患者进行研究。 一旦受试者同意在NIH临床中心参加同种异体HSCT，则受试者将被纳入本方案。迄今为止，已有19名研究参与者及其家庭照顾者接受了潜在参与者的筛选。五对夫妇（患者和护理人员）符合条件并同意入组。三对夫妇已完成研究参与，2人正在接受教育干预。不合格的原因包括：非英语阅读和不一致的护理人员在场。 本研究的结果将指导未来的研究，研究与接受同种异体HSCT的二人组中的常规护理组教育相比，与解决问题教育干预相关的预测因素和结果。

This study is designed to test the potential application of a problem-solving education intervention for patients and family caregivers experiencing allogeneic hematopoietic stem cell transplantation (HSCT). An increase in problem-solving has been shown to decrease distress and may improve symptom distress and health related QOL. The Prepared Family Caregiving intervention, also known as COPE, has demonstrated benefit in cancer patients and their families, however there are limitations to its current application. Only one study has reported the application of this intervention in the acute care setting and no study has been done with patients undergoing HSCT. Subjects are accrued to this protocol once they have agreed to participate in an allogeneic HSCT at the Clinical Center, NIH. To date, 19 research participants and their family caregivers have been screened for potential participation. Five dyads (patient and caregiver) were eligible and agreed to be enrolled. Three dyads have completed study participation and 2 are receiving their education intervention. Reasons for in-eligibility include: non-English reading and inconsistent caregiver presence. The results to this study will guide future research examining predictors and outcomes associated with problem solving education intervention as compared to usual care group education in dyads receiving allogeneic HSCT.