COMPARING THE RESPONSE RATE OF AN ACCELERATED VACCINATION SCHEDULE USING A

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 该研究的目的是在慢性丙型肝炎患者中使用甲型肝炎和B肝炎的加速疫苗接种剂量计划，并将其反应与以完全相同的方式接种疫苗的健康患者进行比较。我们将使用的疫苗是一种联合疫苗，这意味着它可以预防甲型肝炎和B型肝炎病毒。这个项目背后的想法是我们相信丙型肝炎的反应有些受损，不如健康人有效。我们想知道这种加速疫苗接种计划是否能提高对这些疫苗的反应。此外，我们想知道这种疫苗接种计划是否可以用于快速接种不断迁移的人群，例如德克萨斯州美国边境的人群。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The aim of the study is to use an accelerated vaccination dosing chedule for Hepatitis A and B in patients with chronic Hepatitis C and compare their response to healthy patients vaccinated in exactly the same way. The vaccine that we will be using is a combination vaccine, which means it protects against both types of Hepatitis A and B viruses. The idea behind this project is our belief that the response in Hepatitis C is somewhat impaired and not as effective as in healthy people. We want to find out whether this accelerated vaccination schedule can improve the response to these vaccines. In addition we want to find out if this vaccination schedule can be used to rapidly vaccinate populations who are constantly migrating, such as that of the Texas American border.