PLAN FOR OBTAINING INFORMED CONSENT TO USE STORED HUMAN BIOLOGICAL MATERIALS

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这一多中心方案旨在获得适当的知情同意，以存档在所有AACTG试验期间收集的剩余人体生物材料、血液、尿液、组织或其他体液。可能会采集额外的血液样本作为人类DNA的来源，以进行可能的基因分析。这些样本是解决目前无法预测的未来研究问题的重要资源。此外，这些标本代表了独特的队列，这在未来可能无法复制。所有爱滋病临床试验单位的登记人数将不超过50,000人。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This multi-center protocol was designed to obtain the appropriate informed consent to archive left-over human biological materials, blood, urine, tissue, or other body fluids, that are collected during all AACTG trials. An additional blood sample may be collected as a source of human DNA for possible genetic analyses. These samples are an important resource for addressing research questions in the future that cannot be anticipated presently. In addition, the specimens represent unique cohorts, which may not be reproducible in the future. No more than 50,000 subjects will be enrolled all across the AIDS Clinical Trials Units.