LONGITUDINAL STUDY OF OCULAR COMPLICATIONS OF AIDS (SOCA)

这个子项目是许多研究子项目中利用 资源由NIH/NCRR资助的中心拨款提供。子项目和 调查员(PI)可能从NIH的另一个来源获得了主要资金， 并因此可以在其他清晰的条目中表示。列出的机构是 该中心不一定是调查人员的机构。 这项研究将是一项多中心的前瞻性研究，招募了大约2000名艾滋病患者。患者的最佳矫正视力至少有一只眼达到20/100，并且根据1993年疾病控制与预防中心的艾滋病诊断标准被诊断为艾滋病，将有资格参加。主要关注的结果是巨细胞病毒性视网膜炎和其他眼部并发症的发生率和死亡率。次要关注的结果包括艾滋病相关眼病的后遗症(例如视网膜脱离)的发生率、治疗并发症的发生率以及眼睛并发症的长期结果(例如视觉功能、生活质量)。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The study will be a multicenter, prospective study enrolling a cohort of about 2,000 patients with AIDS. Patients will best-corrected visual acuity of at least 20/100 in at least one eye and with a diagnosis of AIDS according to the 1993 CDC diagnostic criteria for AIDS will be eligible for enrollment. The outcome of primary interest are incidence of CMV retinitis and other ocular complications, and mortality. Outcomes of secondary interest include incidence of sequelae of AIDS related eye disease (e.g., retinal detachments), incidence of complications of therapy, and long-term outcomes of ocular complications (e.g., visual function, quality of life).