VITAMINS AND DIET IN TYPE 2 DIABETES

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目及 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本项目的总体目标是研究中等剂量乙醇在磺脲类药物治疗的2型糖尿病患者白天低血糖易感性发病机制中的作用。 研究的具体机制包括（1）可能直接抑制反调节激素释放，（2）直接或间接抑制肝脏葡萄糖生成，和/或（3）胃肠道功能降低，随后延迟碳水化合物吸收。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The overall goals of this project are to investigate the role of moderate doses of ethanol in the pathogenesis of daytime hypoglycemic vulnerability in sulfonylurea-treated patients with type 2 diatetes. Specific mechanisms investigated include (1) possible direct suppression of counterregulatory hormone release, (2) direct or indirect suppression of hepatic glucose production, and/or (3) reduction of gastrointestinal function with a subsequent delay in carbohydrate absorption.