RESEQUENCING THE VARIABLE HUMAN GENOME IN SPORADIC ALS: A NECESSARY PRELUDE TO

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Amyotrophic lateral sclerosis and related motor neuron disorders are neurological diseases that cause muscle weakness. In most patients, the cause is unknown and no effective treatment exists. To study possible causes in a person's genetic material, the Western ALS Consortium [WALS] researchers need blood samples and some basic health-related medical and family history information from patients. This study is collecting the blood samples and information for targeted research into the causes of ALS aiming towards targeted drug treatment in ALS.