Safety Evaluation of Anti-Infective Agents

抗感染药物的安全性评价

• 批准号: 7589910
• 金额: $ 213.51万
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-30 至 2014-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7589910
• 关键词: Safety; Evaluation; Anti; Infective; Agents

The objective of this contract is to support the N IAID in its mission to develop safe and effective therapies for the treatment of infectious diseases caused by Human Immunodeficiency Virus (HIV), Mycobacterium tuberculosis, Plasmodium sp., opportunistic pathogens that infect AIDS patients, and others. The NIAID requires a Safety Evaluation Contract to assess the health and safety potential of new therapies under development by, or with the support of, the Division of AIDS, NIAID. The scope of this effort is to evaluate the toxicity and pharmacokinetics of potential chemical and biological therapies for AIDS and other infectious diseases in various laboratory animal species.

这份合同的目的是支持美国艾滋病署开发安全有效的治疗方法，用于治疗由人类免疫缺陷病毒(HIV)、结核分枝杆菌、疟原虫、感染艾滋病患者的机会性病原体等引起的传染病。NIAID需要一份安全评估合同，以评估由NIAID艾滋病司或在其支持下开发的新疗法的健康和安全潜力。这项工作的范围是评估艾滋病和其他传染病的潜在化学和生物疗法在各种实验动物物种中的毒性和药代动力学。