A PILOT STUDY OF THE CORTICAL BASIS OF MENTALIZING

心智化皮质基础的试点研究

• 批准号: 7608491
• 负责人: THOMAS A ZEFFIRO
• 金额: $ 2.63万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-05-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7608491
• 关键词: Age-Years; Area; Brain; Brain region; Cognitive; Computer Retrieval of Information on Scientific Projects Database; Deception; Disruption; Functional Magnetic Resonance Imaging; Funding; Grant; Institution; Pilot Projects; Process; Recruitment Activity; Research; Research Personnel; Resources; Role; Source; System; United States National Institutes of Health; base; healthy volunteer; relating to nervous system; repetitive transcranial magnetic stimulation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This type A pilot study attempts 1) to identify structural-functional association for mentalizing tasks using functional magnetic resonance imaging (fMRI), and 2) to determine a causal role of frontal brain regions in mentalizing tasks by disruption of such tasks with repetitive transcranial magnetic stimulation (rTMS) of fMRI-identified target areas of the brain. The aim of this research is to identify the neural systems that are critical to support some of the cognitive processes that are involved in deception. Forty healthy, volunteer subjects between 25 and 55 years of age will be recruited for this study.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 本A类先导性研究试图：1）使用功能性磁共振成像（fMRI）来识别心智化任务的结构-功能关联; 2）通过对功能性磁共振成像识别的大脑目标区域进行重复经颅磁刺激（rTMS）来中断此类任务，从而确定额叶脑区在心智化任务中的因果作用。这项研究的目的是确定神经 这些系统对于支持欺骗中涉及的一些认知过程至关重要。本研究将招募40例年龄在25 - 55岁之间的健康志愿者受试者。