SECRETION OF NGAL ON THE SKIN OF PATIENTS TREATED WITH ISOTRETINOIN

异维A酸治疗患者皮肤上 NGAL 的分泌

• 批准号: 7625802
• 负责人: DIANE M. THIBOUTOT
• 金额: $ 1.13万
• 依托单位: PENNSYLVANIA STATE UNIV HERSHEY MED CTR
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7625802
• 关键词: Aftercare; Computer Retrieval of Information on Scientific Projects Database; Funding; Gelatinases; Grant; Institution; Isotretinoin; Outcome; Patients; Pilot Projects; Protein Secretion; Research; Research Personnel; Resources; Serum; Skin; Source; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Gelatinase-Associated Lipocalin (NGAL) on the skin and in the serum (Pilot study) and to determine if there is an increase in NGAL on the skin of patients treated with isotretinoin. The primary outcome will be to quantify the concentration of NGAL on the skin of patients before and after treatment with isotretinoin and to determine the duration of the increase in secretion of this protein.

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 皮肤和血清中的明胶酶相关脂质运载蛋白（NGAL）（初步研究），并确定接受异维甲酸治疗的患者皮肤上的NGAL是否增加。主要结果将是量化异维甲酸治疗前后患者皮肤上NGAL的浓度，并确定该蛋白质分泌增加的持续时间。