PARTNERSHIPS FOR BIOMEDICAL RESEARCH IN ARKANSAS: SCIENCE RESEARCH CORE

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 AR INBRE的科学研究核心由三个科学研究机构提供的服务组成。这些核心设施为全州的研究人员提供了现代生物技术三个关键领域所需的仪器和专业知识。之所以选择这三个领域，是因为每个设施的技术专门知识，特别是仪器设备，即使在一个资金充足的普通研究实验室里也是不常见的。然而，所有这三个设施都代表了分子和细胞水平的研究领域，这些领域每天都在迅速发展。通过使用这些技术进行具体研究和/或收集数据，研究人员可以在自己的实验室中继续和扩展他们的研究项目。 每个生物技术核心设施致力于教育和培训INBRE教师和学生（本科生和研究生）在特定于每个设施的复杂技术。这三个设施及其目标是： 基因组学：提供专业知识和设备，使研究人员能够将基因型和基因表达分析纳入现有研究，并使用最先进的遗传工具设计新的研究。 蛋白质组学：提供专业知识和设备，使研究人员能够使用最先进的仪器研究蛋白质结构。 数字显微镜：提供专业知识和设备，使研究人员能够定位细胞和组织内的大分子，从而更好地评估其在正常和疾病状态下的功能。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The AR INBRE's Science Research Core is comprised of services provided by three scientific research facilities. These core facilities provide investigators throughout the state with access to the instrumentation and expertise needed for three key areas of modern biotechnology. All three areas were chosen because the technical expertise and, especially, the instrumentation of each facility are not commonly available, even in an average, well-funded research laboratory. Yet, all three facilities represent areas of research at the molecular and cellular level in which rapid advances are occurring daily. With access to these technologies for specific studies and/or collection of data, researchers can pursue and extend their research projects in their own laboratories. Each Biotechnology Core facility is committed to the education and training of both INBRE faculty and students (undergraduate and graduate) in the sophisticated technologies specific to each facility. The three facilities and their goals are: Genomics: Provide expertise and equipment to allow researchers to incorporate genotypic and gene expression analyses into existing studies and to design new studies using state-of-the-art genetic tools. Proteomics: Provide expertise and equipment to enable researchers to study protein structure using state-of-the-art instrumentation. Digital Microscopy: Provide expertise and equipment to allow researchers to locate macromolecules within cells and tissues, thereby better assessing their function in normal and diseased states.