Mobilisation of endogenous mesenchymal progenitor cells for growth plate regeneration

动员内源性间充质祖细胞进行生长板再生

• 批准号: nhmrc : 1043426
• 负责人: A/Pr Bruce Foster
• 金额: $ 40.36万
• 依托单位: University of South Australia
• 依托单位国家: 澳大利亚
• 项目类别: Project Grants
• 财政年份: 2013
• 资助国家: 澳大利亚
• 起止时间: 2013-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/mobilisation-endogenous-mesenchymal-plate-regeneration/111576
• 关键词: Mobilisation; endogenous; mesenchymal; progenitor; cells

Growth plate cartilage is responsible for bone growth in children. Its injury is common and is often repaired undesirably by bony tissue which causes significant bone growth defects. This project will develop a biological treatment through mobilising endogenous progenitor cells to enhance growth plate regeneration and prevent bone growth defects, which will allow patients to avoid highly invasive/costly corrective surgeries.

生长板软骨负责儿童的骨骼生长。它的损伤是常见的，并且经常被骨组织不期望地修复，这导致显著的骨生长缺陷。该项目将开发一种生物治疗方法，通过动员内源性祖细胞来增强生长板再生和预防骨生长缺陷，这将使患者避免高度侵入性/昂贵的矫正手术。