NT-3 as an upstream and potentially master regulator promoting bone fracture healing
NT-3 as an upstream and potentially master regulator promoting bone fracture healing
NT-3作为促进骨折愈合的上游和潜在的主调节因子
批准号：
nhmrc : 1127396
负责人：
A/Pr Bruce Foster
金额：
$48.66万
依托单位国家：
澳大利亚
项目类别：
Project Grants
财政年份：
2017
资助国家：
澳大利亚
项目状态：
已结题
起止时间：
2017-01-01 至 2018-12-31
中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
There is a strong clinical need for cost-effective treatments for delayed healing or non-union bone fractures. Our recent data suggest injury site-derived neurotrophin-3 (NT-3) may be an important overall regulator of bone repair by inducing key factors involved in fracture callus formation and remodelling. This project will address roles and mechanisms of endogenous NT-3 in bone repair and the likelihood of exogenous NT-3 protein in promoting bone healing in clinically relevant fracture models.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
NT-3 as an upstream and potentially master regulator promoting bone fracture healing
-
批准号：nhmrc : GNT1127396
-
项目类别：Project Grants
-
资助金额：$71.29万
-
财政年份：2017
-
负责人：A/Pr Bruce Foster
-
依托单位：
Mobilisation of endogenous mesenchymal progenitor cells for growth plate regeneration
-
批准号：nhmrc : 1043426
-
项目类别：Project Grants
-
资助金额：$40.36万
-
财政年份：2013
-
负责人：A/Pr Bruce Foster
-
依托单位：
Bisphosphonate Treatment of Childhood Femoral Head Avascular Necrosis due to Perthes Disease
-
批准号：nhmrc : 632532
-
项目类别：Project Grants
-
资助金额：$91.23万
-
财政年份：2010
-
负责人：A/Pr Bruce Foster
-
依托单位：
Pathophysiology and prevention of methotrexate chemotherapy-induced bone growth defects
-
批准号：nhmrc : 508046
-
项目类别：NHMRC Project Grants
-
资助金额：$41.51万
-
财政年份：2008
-
负责人：A/Pr Bruce Foster
-
依托单位：
Roles of injury-induced inflammatory response in regulating bony repair at injured growth plate cartilage
-
批准号：nhmrc : 453442
-
项目类别：NHMRC Project Grants
-
资助金额：$24.43万
-
财政年份：2007
-
负责人：A/Pr Bruce Foster
-
依托单位：
海外基金
