Coping with Breast Cancer and Treatment: An E-Learning Course for Skills and Stra

描述（由申请人提供）：认知行为压力管理（CBSM）干预措施已被证明可以减少癌症相关的痛苦，促进情绪成长并改善乳腺癌治疗期间的免疫功能。CBSM干预使用经过验证的认知行为技术，如放松和冥想训练、认知重组和沟通技巧训练，以增加积极、适应性应对，通常在小组环境中进行。目前的项目旨在为接受早期乳腺癌辅助治疗的妇女开发一个在线版本的CBSM干预。第一阶段的成果包括开发用户界面和基于web的干预的两个原型模块。这两个模块（“放松入门”和“与医疗保健提供者沟通”）是用Talaria的专有软件创建的，具有高度互动性，并以多媒体格式呈现。两项可用性研究，一项是面对面的，另一项是在线的，共有62名现在和过去的癌症患者，显示出高水平的认可、满意度和易用性。II期的目标是开发整个干预措施，并在随机临床试验中检查其有效性。这10个模块的干预将包括由Talaria经验丰富的临床医生、研究人员、作家、程序员和多媒体专家组成的在线学习团队改编的网络演示的认知行为技术。每个模块都将包括自我评估和有针对性的反馈、说教式心理教育、互动练习和自我监控的机会——所有这些都是根据早期乳腺癌女性的需求量身定制的。此外，有指导的书面自我表露练习将促进情感表达，讨论板将鼓励小组支持。基于网络的干预措施将进行可用性测试，最终产品将在120名乳腺癌辅助治疗妇女的随机临床试验中进行评估。妇女将被随机分配使用为期10周的干预和两周一次的电话评估或单独的电话评估。结果测量包括患者对其应对能力的信心、获益发现、生活质量和癌症相关的痛苦。我们计划将该产品直接销售给癌症患者、癌症护理提供者、医院、诊所和生产癌症药物的制药公司。公共卫生相关性：每年有近20万美国妇女被诊断患有乳腺癌。在接受癌症治疗的过程中，由于压力、治疗副作用、焦虑、抑郁和关系困难，许多患者的生活质量显著下降。我们建议开发一个基于网络版本的认知行为压力管理，这是一种经验支持的乳腺癌妇女干预措施。这种网络干预将是方便的，私人的，并且无论地点或保险范围如何，妇女都可以以低成本获得。

DESCRIPTION (provided by applicant): Cognitive Behavioral Stress Management (CBSM) interventions have been shown to decrease cancer-related distress, foster emotional growth and improve immune functioning during treatment for breast cancer. CBSM interventions use well-validated cognitive behavioral techniques such as relaxation and meditation training, cognitive restructuring, and communication skills training to increase active, adaptive coping and are typically delivered in a group setting. The present project aims to develop an online version of a CBSM intervention for women undergoing adjuvant treatment for early stage breast cancer. Phase I achievements included developing the user interface and two prototype modules of the web-based intervention. These two modules ("Introduction to Relaxation" and "Communication with Healthcare Providers") were created with Talaria's proprietary software, are highly interactive, and are presented in a multimedia format. Two usability studies, one in- person and one online, with 62 current and past cancer patients, demonstrated high levels of approval, satisfaction, and ease-of-use. In Phase II goals are to develop the entire intervention and examine its effectiveness in a randomized clinical trial. This 10-module intervention will consist of cognitive behavioral techniques adapted for web-presentation by Talaria's experienced eLearning team of clinicians, researchers, writers, programmers and multimedia experts. Each module will include self- assessment and targeted feedback, didactic psychoeducation, interactive exercises, and opportunities for self-monitoring-- all tailored to the needs of women with early stage breast cancer. In addition, guided written self-disclosure exercises will promote emotional expression and a discussion board will encourage group support. The web-based intervention will be usability tested and the final product will be evaluated in a randomized clinical trial with a sample of 120 women in adjuvant treatment for breast cancer. Women will be randomly assigned to use the 10-week intervention with biweekly telephone assessments or to the telephone assessments alone. Outcome measures include patients' confidence in their coping abilities, benefit finding, quality of life, and cancer-related distress. We plan to market this product directly to cancer patients, as well as to cancer care providers, hospitals, clinics and pharmaceutical companies that manufacture cancer medications. Public Health Relevance: Nearly 200,000 American women are diagnosed with breast cancer every year. As they go through cancer treatment, many patients experience a significant decline in their quality of life due to stress, treatment side effects, anxiety, depression, and relationship difficulties. We propose to develop a web-based version of Cognitive Behavioral Stress Management, an empirically supported intervention for women with breast cancer. This web intervention will be convenient, private and available for low cost to women regardless of location or insurance coverage.