BACTERIOPHYTOCHROMES: TOOLS FOR UNDERSTANDING PHYTOCHROME SIGNAL TRANSDUCTION

细菌植物色素：了解植物色素信号转导的工具

• 批准号: 7598734
• 负责人: R VIERSTRA
• 金额: $ 0.27万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7598734
• 关键词: Complex; Computer Retrieval of Information on Scientific Projects Database; Family; Funding; Grant; Housing; Institution; Light; Phytochrome; Plants; Research; Research Personnel; Resources; Running; Signal Transduction; Source; Structure; United States National Institutes of Health; chromophore; phycobilin; sensor; tool

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Phytochromes comprise a principal family of red/far-red light sensors in plants. We will attempt structure determination of two new thermostable cyanobacterial phytochromes (comprising the domain which houses the chromophore - phycocyanobilin). This construct photoconverts and is only 23.6 kDa and we would like to also determine its Pr andf Pfr forms upon red light exposure.On the long run we would like to eventually determine homodimer structures of these domains and the complexes with PHY signaling domains.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 光敏色素是植物中红光/远红光传感器的主要家族。我们将尝试确定两种新的耐热蓝细菌光敏色素（包括容纳发色团 - 藻蓝蛋白的结构域）的结构。该构建体可进行光转换，大小仅为 23.6 kDa，我们还希望确定其在红光照射下的 Pr 和 f Pfr 形式。从长远来看，我们希望最终确定这些结构域的同二聚体结构以及与 PHY 信号结构域的复合物。