NEUROPSYCHOLOGICAL PROGESSION IN NEW ONSET EPILEPSY

该子项目是利用 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。列出的机构是 研究中心，而研究中心不一定是研究者所在的机构。 该项目涉及75名新发癫痫儿童和65名健康的一级表亲对照（年龄8-18岁）的评估（定量MRI，神经心理学，精神病学）。目的是确定癫痫发作时的认知状态、脑结构和精神病史，并在两年的时间间隔内跟踪认知、脑和情感行为发育的过程。所有基线测试已经完成，我们已经进入项目的前瞻性阶段，受试者保留率>90%。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This project involves evaluation (quantitative MRI, neuropsychological, psychiatric) of 75 children with new onset epilepsy and 65 healthy first degree cousin controls (ages 8-18). The purpose is to determine the status of cognition, brain structure and psychiatric history at onset of epilepsy and to follow the course of cognitive, brain, and emotional-behavioral development over a two year interval. All baseline testing has been completed and we are well into the prospective phase of the project with >90% subject retention.