DIM STUDY

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Hypothesis " BioResponse DIM will be associated with a reduction or clearance of anal infection with human papillomavirus in HIV-infected and HIV-uninfected MSM without evidence of dysplasia Primary Objective " To evaluate the presence of HPV after 12 weeks of treatment with BR-DIM Secondary Objectives " To evaluate the safety and tolerability of BR-DIM. " To evaluate the effect of DBR DIM on the urinary ratio of 2-hydoxyestrone /16 ¿¿ hydroxyestrone metabolites