Data Management & Statistical Core

数据管理和统计核心的项目摘要/摘要 数据管理和统计(DMS)核心的总体目标是支持 预防艾滋病毒携带者的HPV相关癌症：巴西、墨西哥、波多黎各和这三个国家 由该小组通过统计设计、数据管理和分析进行的临床试验，并 为将公布研究结果的研究人员提供分析专业知识和教育支持 通过出版手稿和国家/国际演示文稿。这从分析设计开始 和每个临床试验提交所需的样本量的确定，继续监测 积累数据，并通过统计分析、手稿开发完成，最终， 发表结果，包括表格、数字和科学结论。DMS核心总监迈克尔博士 Schell将通过在生物统计学方面的讲座和指导向成员和 拉丁美洲和加勒比伙伴网站的研究人员，目标是建设拉丁美洲和加勒比地区的专门知识和能力 美洲/加勒比合作伙伴网站将领导未来的试验。他将与和合作开展这些工作 Tonatieh Barrientos Gutierrez博士的指导，他是美国国立卫生研究院的流行病学家和生物统计学家 公共卫生，墨西哥。

PROJECT SUMMARY/ABSTRACT FOR DATA MANAGEMENT AND STATISTICAL CORE The overall goals of the Data Management and Statistical (DMS) Core are to support the Partnership for Prevention of HPV-Associated Cancers in People Living with HIV: Brazil, Mexico, Puerto Rico and the three clinical trials to be conducted by this group through statistical design, data management, and analysis, and to provide analytical expertise and educational support to the researchers who will promulgate the findings through manuscripts for publication and national/international presentations. This begins with analytical design and sample size determination as needed for each clinical trial submission, continues with monitoring of accumulating data, and reaches completion with statistical analyses, manuscript development, and, ultimately, publication of results, including tables, figures, and scientific conclusions. The DMS Core Director, Dr. Michael Schell, will provide education and training through lectures and mentorship in biostatistics to members and research staff of the LAC partner sites, with the goal of building the expertise and capacity of the Latin America/Caribbean partner sites to lead future trials. He will conduct these efforts in collaboration with and mentorship of Dr. Tonatiuh Barrientos Gutierrez, an epidemiologist and biostatistician from National Institute of Public Health, Mexico.