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BEHAVIORAL PREPARATION FOR TREATING FIBROMYALGIA

治疗纤维肌痛的行为准备

基本信息

批准号：
7610877
负责人：
Akiko Okifuji
金额：
$ 48.13万
依托单位：
UNIVERSITY OF UTAH
依托单位国家：
美国
项目类别：
财政年份：
2004
资助国家：
美国
起止时间：
2004-06-01 至 2012-03-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7610877
关键词：
Address Adopted Affect Aftercare Behavior Behavioral Belief Chronic Clinic Clinical Clinical Trials Cognition Cognitive Coping Skills Distress Drops Education Evaluation Exercise Exhibits Fibromyalgia Goals Group Meetings Habits Hand Home environment Hour Individual Differences Mediating Mediation Medical Modeling Motivation Outcome Pain Pain management Patients Pharmaceutical Preparations Phase Physical Education Physical therapy Physical therapy exercises Population Preparation Process Protocols documentation Questionnaires Readiness Rehabilitation therapy Research Residual state Rheumatism Self Efficacy Self Management Series Serotonin Sleep Social support Stress Symptoms Testing Training Programs Treatment Protocols Welts base chronic pain clinical efficacy compliance behavior conditioning coping demographics depressed depression disability efficacy testing follow-up improved lectures multidisciplinary programs psychologic sedentary skills skills training treatment effect treatment response willingness

项目摘要

DESCRIPTION: Fibromyalgia syndrome (FMS) is a prevalent, chronic musculoskeletal pain disorder. Although no treatment has been shown to be universally effective, research suggests that a multimodal rehabilitative approach including active physical exercise and coping skill training reduces various symptoms of FMS. Nevertheless, there is large variability in treatment response. Since the rehabilitative approach requires patients to adopt a set of new perspectives and behaviors, the clinical benefit of such approach largely depends upon patient readiness and willingness to comply with the regimen. Past research suggests that successful outcomes require patient intent to change, efficacious beliefs about change, and ability to undertake process of change. In this amended application, we propose to evaluate the clinical efficacy of coping skill training and motivation enhancement therapy to prepare sedentary FMS patients to a rehabilitative approach. A total of 300 patients will be screened. Eligible patients will undergo a 10 2-hour weekly treatment sessions consisting of active exercise, physical therapy education, and one of the three behavioral preparation programs: Coping Skill Training program (CST), Motivation Enhancement program (MET), or Educational Lectures (EDS). Ten hours of the therapy hours across the first 6 weeks and one additional hour at the end of the program will be dedicated to behavioral preparation. All patients will receive one hour active physical exercise from Week 5 to Week10 and one hour physical education in Week 7 through Week 9. A comprehensive evaluation including medical, physical, and psychological assessments at the clinic and a home assessment protocol examining daily symptoms, activity levels, and sleep quality for one week will be performed at pre-treatment, post-treatment, and 6 month follow-up phases. At 12 month follow-up, each patient will undergo the home assessment protocol and questionnaire assessment. We will also delineate factors associated with clinically meaningful outcomes for each preparation program and to test mediation paths to better understand the mechanisms of clinical improvement via rehabilitation. We expect that results from this study will facilitate better understanding of how motivation enhancement augments clinical benefit of rehabilitative approach for many chronic pain conditions.

描述：纤维肌痛综合征 (FMS) 是一种普遍存在的慢性肌肉骨骼疼痛疾病。尽管尚无治疗方法被证明是普遍有效的，但研究表明，包括积极体育锻炼和应对技能训练在内的多模式康复方法可以减少 FMS 的各种症状。然而，治疗反应存在很大差异。由于康复方法要求患者采取一系列新的观点和行为，因此这种方法的临床益处在很大程度上取决于患者遵守治疗方案的准备程度和意愿。过去的研究表明，成功的结果需要患者有改变的意愿、对改变的有效信念以及进行改变过程的能力。在这个修改后的申请中，我们建议评估应对技能训练和动机增强疗法的临床疗效，以帮助久坐的 FMS 患者做好康复治疗的准备。总共将筛查300名患者。符合条件的患者将接受 10 次每周 2 小时的治疗课程，包括主动锻炼、物理治疗教育和三个行为准备计划之一：应对技能训练计划 (CST)、动机增强计划 (MET) 或教育讲座 (EDS)。前 6 周的 10 小时治疗时间和项目结束时的额外 1 小时将专门用于行为准备。所有患者将在第5周至第10周接受一小时的主动体育锻炼，并在第7周至第9周接受一小时的体育教育。在治疗前、治疗后和6个月的随访阶段将进行包括临床医学、身体和心理评估在内的综合评估以及为期一周的家庭评估方案，检查每日症状、活动水平和睡眠质量。在 12 个月的随访中，每位患者都将接受家庭评估方案和问卷评估。我们还将为每个准备计划描述与临床有意义的结果相关的因素，并测试调解路径，以更好地了解通过康复改善临床的机制。我们期望这项研究的结果将有助于更好地理解动机增强如何增强许多慢性疼痛疾病康复方法的临床益处。