UND COMPUTATIONAL CHEMISTRY AND BIOLOGY CORE

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This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Bioinformatics Core is designed to enhance the states access to computational and electronic resources supporting biomedical research. The aims are to: 1) support the computational needs of INBRE investigators through the Computational Chemistry and Biology Network; 2) Achieve sustainability of the CCBN by transitioning from an SGI/IRIX-platform to a PC/LINUX platform, and by instituting a service fee plan; and 3) Enhance the electronic resources and databases for the statewide INBRE network. The transparent nature of electronic resources makes substantive cooperation between the two research universities in North Dakota feasible. With affordable access as the guiding principle, investigators at UND and NDSU and the wider scientific network benefit from increased resources at their disposal, and institutions benefit by being able to lower costs through consortium agreements. In order to meet these needs and to keep the cost of supporting the CCBN under control, the CCBN will undergo a major transformation from its current SGI/IRIX platform to a PC/LINUX platform. As this happens, remote users will be able to access state-of-the-art molecular modeling with standard PCs, and tap into the computing power of the existing and planned servers and PC clusters. The implementation of a user fee system over five years that will be meet the future maintenance needs of the CCBN. As electronic resources purchased during BRIN Phase I are institutionalized, this allows the INBRE library consortium to evaluate and purchase additional electronic journals and databases that will serve the biomedical research community. Special attention will be given to provide the INBRE investigators access to the electronic resources they will need to do their research.