COBRE: UVM: CORE D: TRANSLATIONAL NEUROSCIENCE TRAINING

这个子项目是许多研究子项目中的一个 由NIH/NCRR资助的中心赠款提供的资源。子项目和 研究者（PI）可能从另一个NIH来源获得了主要资金， 因此可以在其他CRISP条目中表示。所列机构为 研究中心，而研究中心不一定是研究者所在的机构。 核心是在其第六年的支持，与提供一个环境，鼓励在转化神经科学的职业发展的目标。 在此之前，核心基金提供津贴，支持医学生（科茨先生、凯利先生、乔利诺女士、奎克女士和潘女士）的研究金，他们分别与马维、韦尔曼、马维、西波拉和埃肯斯坦博士一起进行全职实验室研究。 科茨先生发表了一篇论文，并在国家会议上作了介绍。 这一成功促使科茨先生进入UVM的MD/PhD课程。 Kelley先生已毕业，目前是北卡罗来纳州大学的住院医师。 奎克女士发表了一篇论文，乔利诺女士发表了两篇论文。 潘女士已经毕业，并提交了一份出版物，预计她将与他人合著另一份。两名MD/PhD学生Joseph Cheung和Julia Cambron今年通过翻译核心获得了支持。 已经组织了一个说明转化神经科学研究进展的课程。 该课程提供了对单一神经系统疾病研究的深入分析。 所承保的疾病每年都在变化。 过去的疾病包括帕金森氏病，多发性硬化症，精神分裂症和肌萎缩侧索硬化症和脑血管疾病。 今年的课程将集中在自闭症谱系障碍。该课程包括12个每周一次的会议，从临床研究到基础分子方法。 来自神经病学，神经外科，心理学，医学和解剖学与神经生物学系的教师在这个团队授课的课程中合作。 此外，每年有1至4名外部演讲者提供讲座（哈佛大学的Michael Moskowitz博士去年提供了讲座）。 一个本科神经科学暑期奖学金计划已经建立。 本科生进行10周的研究，阅读主要文献，并参加COBRE教师的讲座。 今年有110多名学生（大部分来自UVM以外的机构）申请，其中8人被录取。 我们正在重点加强代表性不足的少数民族的申请，今年接受的八个申请中有两个属于这一类。 UVM的研究生院正在积极支持这一努力。我们过去的几个学生已经继续攻读博士学位。研究生课程，包括两个谁加入了我们的神经科学计划。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The Core is in its sixth year of support, with the goal of providing an environment that encourages career development in translational neuroscience. Previously, the core had provided the stipend to support a research fellowship for medical students (Mr. Coates, Mr. Kelley, Ms. Ciolino, Ms. Quick and Ms. Pan) who conducted full-time bench research with Drs. Mawe, Wellman, Mawe, Cipolla and Eckenstein, respectively. Mr. Coates published one paper and presented at national meetings. This success motivated Mr. Coates to enter UVM's MD/PhD program. Mr. Kelley has graduated and is currently a resident at the University of North Carolina. Ms. Quick's work has resulted in one published paper while Ms. Ciolino has published two papers. Ms. Pan has graduated with one submitted publication, and she is expected to co-author another. Two MD/PhD students, Joseph Cheung and Julia Cambron, have been supported this year through the Translational Core. A course illustrating the progress of translational neuroscience research has been organized. The course provides an in-depth analysis of research into a single neurological disease. The disease to be covered changes every year. Past disease entities covered include Parkinson's Disease, Multiple Sclerosis, Schizophrenia and Amyotrophic Lateral Sclerosis and Cerebrovascular Diseases. This year's course will focus on Autism Spectrum Disorders. The course consists of 12 weekly sessions ranging from clinical research to basic molecular approaches. Faculty from the Departments of Neurology, Neurosurgery, Psychology, Medicine and Anatomy & Neurobiology collaborate in this team-taught course. In addition, one to four outside speakers contribute lecture every year (Dr. Michael Moskowitz of Harvard University contributed last year). An Undergraduate Neuroscience Summer fellowship program has been established. Undergraduates perform 10 weeks of research, read primary literature and attend lectures given by COBRE faculty. This year over 110 students (most from institutions outside of UVM) applied, and 8 were accepted. We are focusing on enhancing applications from underrepresented minorities, and two of the eight accepted for this year fall into this category. UVM's Graduate College is actively supporting this effort. Several of our past students have gone on to Ph.D. graduate programs, including two who have joined our Neurosciences program.