COBRE: UVM: CORE D: TRANSLATIONAL NEUROSCIENCE TRAINING

该子项目是利用NIH/NCRR资助的中心赠款提供的资源的许多研究子项目之一。子项目和研究者（PI）可能从另一个NIH来源获得主要资金，因此可以在其他CRISP条目中表示。所列机构为中心，不一定是研究者所在机构。这个核心是在其第四年的支持，其目标是提供一个智力环境，鼓励在转化神经科学的职业发展。 此前，该核心为两名医学生（科茨和凯利）提供了研究奖学金，他们与Mawe和Wellman博士一起进行了全职实验室研究。科茨先生发表了一篇论文，并在国家会议上作了介绍。这一成功促使科茨先生进入UVM的MD/PhD课程。Kelley先生已毕业，目前是北卡罗来纳州大学的住院医师。在这一年里，核心基金为两名医科学生（Ciolino和Quick）提供了额外的研究金支助。这些学生与Mawe和Cipolla博士一起进行了研究。奎克女士的工作发表了一篇论文，乔利诺女士正在继续她的研究金。 今年，潘传菊女士在埃肯斯坦博士的实验室进行研究，预计她将共同撰写两篇论文。此外，今年Meagan Costedio博士正在加里Mawe博士的实验室进行研究。她的研究包括一个项目，以确定血清素浓度和信号是否在憩室病患者的结肠中改变，以及它们与憩室炎患者的结肠相比如何。 已经组织了一个说明转化神经科学研究进展的课程。该课程提供了对单一神经系统疾病研究的深入分析。所承保的疾病每年都在变化。过去的疾病实体包括帕金森氏病，多发性硬化症和精神分裂症。今年的课程将集中在肌萎缩侧索硬化症。该课程包括12个每周一次的会议，从临床研究到基础分子方法。来自神经病学，神经外科，心理学，医学和解剖学与神经生物学系的教师在这个团队授课的课程中合作。 此外，今年有两名外部演讲者提供了讲座。 一个本科神经科学暑期奖学金计划已经建立。本科生进行10周的研究，阅读主要文献，并参加COBRE教师的讲座。大约40名学生（大多数来自与UVM不同的机构）申请，大约8名被选中。有几个人已经拿到了博士学位。研究生课程。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This Core is in its 4th year of support, with the goal to provide an intellectual environment encouraging career development in translational neuroscience. Previously, the core had provided the stipend to support a research fellowship for two medical students (Coates and Kelley) who conducted full-time bench research with Drs. Mawe and Wellman. Mr. Coates¿ published one paper and presented at national meetings. This success motivated Mr. Coates to enter UVM¿s MD/PhD program. Mr. Kelley has graduated and is currently a resident at the University of North Carolina. During the year the core provided additional fellowship support for two medical students (Ciolino and Quick). These students have conducted research with Drs. Mawe and Cipolla. Ms. Quick's work has resulted in one published paper and Ms. Ciolino is continuing her fellowship. This year, Ms. Chuan-Ju Pan is conducting research in Dr. Eckenstein's laboratory, and it is expected that she will co-author two publications. Additionally, this year Dr. Meagan Costedio is conducting research in Dr. Gary Mawe's lab. Her research consists of a project to determine if serotonin concentrations and signaling are altered in the colons of people with diverticulosis, and how they compare with colons of people with diverticulitis. A course illustrating the progress of translational neuroscience research has been organized. The course provides an in-depth analysis of research into a single neurological disease. The disease to be covered changes every year. Past disease entities covered include Parkinson's Disease, Multiple Sclerosis and Schizophrenia. This year's course will focus on Amyotrophic Lateral Sclerosis. The course consists of 12 weekly sessions ranging from clinical research to basic molecular approaches. Faculty from the Departments of Neurology, Neurosurgery, Psychology, Medicine and Anatomy & Neurobiology collaborate in this team-taught course. In addition, two outside speakers contributed lectures this year. An Undergraduate Neuroscience Summer fellowship program has been established. Undergraduates perform 10 weeks of research, read primary literature and attend lectures given by COBRE faculty. Approximately 40 students (most from institutions different from UVM) apply, and approximately 8 are selected. Several have gone on to Ph.D. graduate programs.