COBRE: UVM: CORE D: TRANSLATIONAL NEUROSCIENCE TRAINING

该子项目是利用 NIH/NCRR 资助的中心拨款提供的资源的众多研究子项目之一。子项目和研究者 (PI) 可能已从另一个 NIH 来源获得主要资金，因此可以在其他 CRISP 条目中出现。列出的机构是中心的机构，不一定是研究者的机构。该核心已进入第四个年头，其目标是提供一个鼓励转化神经科学职业发展的智力环境。 此前，该核心曾为两名医学生（科茨和凯利）提供研究奖学金，他们与 Drs. 一起进行全职实验室研究。马维和韦尔曼。科茨先生发表了一篇论文并在全国会议上发表了演讲。这一成功激励 Coates 先生进入 UVM 的医学博士/博士课程。凯利先生已毕业，目前是北卡罗来纳大学的住院医师。这一年，核心为两名医学生（Ciolino 和 Quick）提供了额外的奖学金支持。这些学生与博士进行了研究。玛维和西波拉。奎克女士的工作发表了一篇论文，西奥利诺女士正在继续她的研究金。 今年，潘川菊女士在埃肯斯坦博士的实验室进行研究，预计她将与人共同撰写两篇出版物。此外，今年 Meagan Costedio 博士正在 Gary Mawe 博士的实验室进行研究。她的研究包括一个项目，以确定憩室病患者结肠中的血清素浓度和信号是否发生改变，以及它们与憩室炎患者的结肠相比如何。 已经组织了一门展示转化神经科学研究进展的课程。该课程对单一神经系统疾病的研究进行深入分析。承保的疾病每年都会发生变化。涵盖的既往疾病包括帕金森病、多发性硬化症和精神分裂症。今年的课程将重点关注肌萎缩侧索硬化症。该课程包括 12 周课程，内容涵盖临床研究到基本分子方法。来自神经病学、神经外科、心理学、医学以及解剖学和神经生物学系的教师在这门团队授课的课程中合作。 此外，今年还有两位外部演讲者发表了演讲。 本科生神经科学夏季奖学金计划已经建立。本科生进行 10 周的研究、阅读主要文献并参加 COBRE 教师的讲座。大约 40 名学生（大多数来自 UVM 以外的院校）申请，大约 8 名被选中。一些人继续攻读博士学位。研究生课程。

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This Core is in its 4th year of support, with the goal to provide an intellectual environment encouraging career development in translational neuroscience. Previously, the core had provided the stipend to support a research fellowship for two medical students (Coates and Kelley) who conducted full-time bench research with Drs. Mawe and Wellman. Mr. Coates¿ published one paper and presented at national meetings. This success motivated Mr. Coates to enter UVM¿s MD/PhD program. Mr. Kelley has graduated and is currently a resident at the University of North Carolina. During the year the core provided additional fellowship support for two medical students (Ciolino and Quick). These students have conducted research with Drs. Mawe and Cipolla. Ms. Quick's work has resulted in one published paper and Ms. Ciolino is continuing her fellowship. This year, Ms. Chuan-Ju Pan is conducting research in Dr. Eckenstein's laboratory, and it is expected that she will co-author two publications. Additionally, this year Dr. Meagan Costedio is conducting research in Dr. Gary Mawe's lab. Her research consists of a project to determine if serotonin concentrations and signaling are altered in the colons of people with diverticulosis, and how they compare with colons of people with diverticulitis. A course illustrating the progress of translational neuroscience research has been organized. The course provides an in-depth analysis of research into a single neurological disease. The disease to be covered changes every year. Past disease entities covered include Parkinson's Disease, Multiple Sclerosis and Schizophrenia. This year's course will focus on Amyotrophic Lateral Sclerosis. The course consists of 12 weekly sessions ranging from clinical research to basic molecular approaches. Faculty from the Departments of Neurology, Neurosurgery, Psychology, Medicine and Anatomy & Neurobiology collaborate in this team-taught course. In addition, two outside speakers contributed lectures this year. An Undergraduate Neuroscience Summer fellowship program has been established. Undergraduates perform 10 weeks of research, read primary literature and attend lectures given by COBRE faculty. Approximately 40 students (most from institutions different from UVM) apply, and approximately 8 are selected. Several have gone on to Ph.D. graduate programs.