Continued Development for The Image-guided Surgical Toolkit Project (IGSTK)

图像引导手术工具包项目 (IGSTK) 的持续开发

• 批准号: 7560003
• 负责人: Kevin R. Cleary
• 金额: $ 46.97万
• 依托单位: GEORGETOWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2012-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7560003
• 关键词: Arizona; Biopsy; Businesses; Canada; Clinical; Clinical Trials; Communication; Communities; Computer software; Computers; Development; Devices; District of Columbia; Doctor of Philosophy; Documentation; Electromagnetics; Electronic Mail; FDA approved; Feedback; Goals; Grant; Image; Image-Guided Surgery; Intervention; Licensing; Lung; Maintenance; Medical; Medical Imaging; Modeling; Needles; New York; Ontario; Operative Surgical Procedures; Optics; Patient Care; Patients; Phase; Pilot Projects; Principal Investigator; Process; Research; Research Ethics Committees; Research Personnel; Scientist; Small Business Technology Transfer Research; Software Engineering; System; Technology; Testing; Universities; Validation; base; clinical application; computer science; experience; interest; medical schools; meetings; member; minimally invasive; open source; pilot trial; professor; programs; radiologist; response; software development; software systems; symposium; tool; web site

DESCRIPTION (provided by applicant): This proposal is to continue to develop, maintain, test, and evaluate the Image-Guided Surgical Toolkit (IGSTK). IGSTK is an open source software project that provides the basic components to develop an image-guided system. The initial version of the software was released to the public in February 2006 at the SPIE Medical Imaging Conference in San Diego and we continue to receive positive feedback from the user community. The software is currently available on the IGSTK web site for free download by any interested party under the BSD open source license. The software was developed under a Phase II STTR grant over the last two years, which will expire in August 2006. The ultimate goal of this project is to provide a robust, open source toolkit for rapidly developing image- guided software for research and clinical applications. To realize this goal, we need to continue to develop the toolkit and support the user community. Therefore, we are submitting this R01 proposal in response to the PAR-05-057 announcement "Continued Development and Maintenance of Software". The proposal is targeted at user support, software extensions, and the development of an FDA approved image-guided application and initial clinical trial. This is a three year project with four specific aims: 1. Support the IGSTK user community by responding to email requests, fixing bugs, developing documentation, and holding an annual users meeting at the SPIE Medical Imaging conference 2. Extend the existing software by developing: a. Multi-threading for better handling of multiple devices and heavy processing loads along with inter-process communication to simplify safe integration of IGSTK with other software packages b. Validation tools for the state machine model that the toolkit is based on 3. Develop an application template and programming guide to make it easier for new users to develop applications using the toolkit 4. Develop an image-guided application for lung biopsy incorporating electromagnetic tracking of the needle tip and pursue FDA/IRB approval for a pilot trial of 10 patients The completion of this project will provide an open source software system that will allow researchers to rapidly develop image-guided applications that will ultimately benefit patient care.

描述（由申请人提供）：该提案旨在继续开发、维护、测试和评估图像引导手术工具包（IGSTK）。 IGSTK 是一个开源软件项目，提供开发图像引导系统的基本组件。该软件的初始版本于 2006 年 2 月在圣地亚哥 SPIE 医学成像会议上向公众发布，我们不断收到用户社区的积极反馈。该软件目前可在 IGSTK 网站上使用，任何感兴趣的团体均可根据 BSD 开源许可证免费下载。该软件是在过去两年中根据第二阶段 STTR 拨款开发的，该拨款将于 2006 年 8 月到期。该项目的最终目标是提供一个强大的开源工具包，用于快速开发用于研究和临床应用的图像引导软件。为了实现这一目标，我们需要继续开发工具包并支持用户社区。因此，我们提交此 R01 提案是为了响应 PAR-05-057 公告“软件的持续开发和维护”。该提案的目标是用户支持、软件扩展以及 FDA 批准的图像引导应用程序和初步临床试验的开发。这是一个为期三年的项目，有四个具体目标： 1. 通过响应电子邮件请求、修复错误、开发文档以及在 SPIE 医学成像会议上举行年度用户会议来支持 IGSTK 用户社区 2. 通过开发以下内容来扩展现有软件：多线程可以更好地处理多个设备和繁重的处理负载，以及进程间通信以简化 IGSTK 与其他软件包的安全集成 b．该工具包所基于的状态机模型的验证工具 3. 开发应用程序模板和编程指南，使新用户更容易使用该工具包开发应用程序 4. 开发用于肺活检的图像引导应用程序，结合针尖的电磁跟踪，并寻求 FDA/IRB 批准对 10 名患者进行试点试验 该项目的完成将提供一个开源软件系统，使研究人员能够快速开发图像引导应用程序 这最终将有利于患者护理。