Modulation of feeding through pharmacological targeting of the relaxin-3 receptor RXFP3
Modulation of feeding through pharmacological targeting of the relaxin-3 receptor RXFP3
批准号:
nhmrc : 1066369
负责人:
Dr Joseph Nicolazzo
金额:
$39.0万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2014
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2014-01-01 至 2017-12-31
中文摘要
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英文摘要
Relaxin-3 is a neuropeptide that regulates a number of physiological processes, including food intake, suggesting that the relaxin-3 receptor RXFP3 may be a new target for treatment of eating disorders such as obesity. This project will develop new selective and high-affinity ligands for RXFP3, which will be critical pharmacological tools for the preclinical studies and evaluation of this system.
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