Pediatric Infectious Diseases Research Training

儿科传染病研究培训

• 批准号: 7640533
• 负责人: MICHAEL R WESSELS
• 金额: $ 30.93万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-20 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7640533
• 关键词: Childhood; Infectious Diseases Research; Research Training

DESCRIPTION (provided by applicant): This application seeks support for a training program that prepares highly qualified pediatricians and selected Ph.D. postdoctoral scientists to assume leadership positions as investigators in Pediatric Infectious Diseases. Based in the Division of Infectious Diseases at Children's Hospital Boston, the program takes advantage of the rich academic and research resources of Harvard Medical School, Harvard School of Public Health, and affiliated teaching hospitals to bring together outstanding didactic experiences and research opportunities relevant to infectious diseases of children. Support for a total of six positions per year is requested (four M.D. and two Ph.D.). Pediatricians enter the program for a minimum of three years of integrated clinical and research training that includes at least two years of supervised research under the mentorship of a member of the teaching faculty. Research training of pediatricians is fully integrated with that of Ph.D. postdoctoral trainees in the laboratories of the teaching faculty. The 23 members of the teaching faculty are accomplished investigators and experienced mentors chosen from the Division of Infectious Diseases at Children's Hospital Boston and five affiliated units at other Harvard institutions. Under the guidance of the research mentor and the Program Steering Committee, an individualized curriculum is designed for each trainee in one of three broad areas of investigation: microbial pathogenesis, host response and vaccines, or epidemiology and health policy. Trainees in the epidemiology and health policy pathway have the opportunity to earn a Master's of Public Health degree from the Harvard School of Public Health as an integral part of the training program. Trainees in the other pathways also receive training in epidemiology, biostatistics, clinical trial design, and analytic methods. All trainees have seminars and tutorials in grant preparation and scientific writing that supplement the mentored research experience. An individual Scholarship Oversight Committee is appointed for each trainee to monitor progress and to provide career guidance. During the second or third year, trainees are expected to present their work at national meetings, to prepare one or more manuscripts for publication, and, in most cases, to apply for a K08 or other career development award to support the transition to independence as an investigator. Relevance: The goal of the training program is to train pediatricians and Ph.D. postdoctoral scientists for careers as researchers who will address the present and future challenges of childhood infections. Well- trained investigators in Pediatric Infectious Diseases are urgently needed to meet the ongoing and emerging threats to child health of congenital HIV infection, childhood malaria and tuberculosis, diarrheal diseases, and respiratory infections-critical problems that are further complicated by increasing antimicrobial resistance and societal opposition to childhood vaccines.

描述(由申请者提供)：本申请寻求对培训计划的支持，该计划旨在培养高素质的儿科医生和精选的博士后科学家，担任儿科传染病研究人员的领导职位。该项目总部设在波士顿儿童医院传染病科，利用哈佛医学院、哈佛公共卫生学院及其附属教学医院丰富的学术和研究资源，汇集与儿童传染病相关的优秀教学经验和研究机会。要求每年总共支助六个职位(四个医学博士和两个博士)。儿科医生参加该计划至少需要三年的临床和研究综合培训，其中包括至少两年在一名教师的指导下进行的监督研究。儿科医生的研究培训与教师实验室的博士后培训完全结合起来。23名教员是从波士顿儿童医院传染病科和哈佛其他机构的五个附属单位挑选出来的经验丰富的研究人员和导师。在研究导师和项目指导委员会的指导下，为每个受训人员设计了三个广泛调查领域之一的个性化课程：微生物发病机制、宿主反应和疫苗，或流行病学和卫生政策。作为培训计划的组成部分，流行病学和卫生政策领域的学员有机会从哈佛公共卫生学院获得公共卫生硕士学位。其他途径的受训者还接受流行病学、生物统计学、临床试验设计和分析方法方面的培训。所有受训者都有赠款准备和科学写作方面的研讨会和教程，以补充指导研究的经验。为每个受训人员指定了一个奖学金监督委员会，以监测进展情况并提供职业指导。在第二年或第三年，受训人员将在全国会议上介绍他们的工作，准备一份或多份手稿以供出版，并在大多数情况下申请K08或其他职业发展奖，以支持向独立的调查员过渡。相关性：该培训计划的目标是培训儿科医生和博士后科学家，使他们成为研究人员，解决儿童感染目前和未来的挑战。迫切需要训练有素的儿科传染病研究人员，以应对先天性艾滋病毒感染、儿童疟疾和结核病、腹泻疾病和呼吸道感染等对儿童健康的持续和新出现的威胁--这些关键问题因抗菌素耐药性的增加和社会对儿童疫苗的反对而变得更加复杂。