Pediatric Infectious Diseases Research Training

儿科传染病研究培训

• 批准号: 7433415
• 负责人: MICHAEL R WESSELS
• 金额: $ 29.21万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-20 至 2013-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7433415
• 关键词: Childhood; Infectious Diseases Research; Research Training

DESCRIPTION (provided by applicant): This application seeks support for a training program that prepares highly qualified pediatricians and selected Ph.D. postdoctoral scientists to assume leadership positions as investigators in Pediatric Infectious Diseases. Based in the Division of Infectious Diseases at Children's Hospital Boston, the program takes advantage of the rich academic and research resources of Harvard Medical School, Harvard School of Public Health, and affiliated teaching hospitals to bring together outstanding didactic experiences and research opportunities relevant to infectious diseases of children. Support for a total of six positions per year is requested (four M.D. and two Ph.D.). Pediatricians enter the program for a minimum of three years of integrated clinical and research training that includes at least two years of supervised research under the mentorship of a member of the teaching faculty. Research training of pediatricians is fully integrated with that of Ph.D. postdoctoral trainees in the laboratories of the teaching faculty. The 23 members of the teaching faculty are accomplished investigators and experienced mentors chosen from the Division of Infectious Diseases at Children's Hospital Boston and five affiliated units at other Harvard institutions. Under the guidance of the research mentor and the Program Steering Committee, an individualized curriculum is designed for each trainee in one of three broad areas of investigation: microbial pathogenesis, host response and vaccines, or epidemiology and health policy. Trainees in the epidemiology and health policy pathway have the opportunity to earn a Master's of Public Health degree from the Harvard School of Public Health as an integral part of the training program. Trainees in the other pathways also receive training in epidemiology, biostatistics, clinical trial design, and analytic methods. All trainees have seminars and tutorials in grant preparation and scientific writing that supplement the mentored research experience. An individual Scholarship Oversight Committee is appointed for each trainee to monitor progress and to provide career guidance. During the second or third year, trainees are expected to present their work at national meetings, to prepare one or more manuscripts for publication, and, in most cases, to apply for a K08 or other career development award to support the transition to independence as an investigator. Relevance: The goal of the training program is to train pediatricians and Ph.D. postdoctoral scientists for careers as researchers who will address the present and future challenges of childhood infections. Well- trained investigators in Pediatric Infectious Diseases are urgently needed to meet the ongoing and emerging threats to child health of congenital HIV infection, childhood malaria and tuberculosis, diarrheal diseases, and respiratory infections-critical problems that are further complicated by increasing antimicrobial resistance and societal opposition to childhood vaccines.

描述（由申请人提供）：本申请旨在支持一项培训计划，该计划旨在培养高素质的儿科医生和选定的博士博士后科学家，以担任儿科传染病研究人员的领导职位。该项目以波士顿儿童医院传染病科为基地，利用哈佛医学院、哈佛公共卫生学院和附属教学医院丰富的学术和研究资源，将与儿童传染病相关的优秀教学经验和研究机会结合在一起。每年总共需要六个职位的支持（四个医学博士和两个博士）。儿科医生进入该项目至少要接受三年的综合临床和研究培训，其中包括至少两年在一名教师的指导下进行监督研究。儿科医师的科研培训与博士博士后的科研培训在教师实验室全面整合。教学团队的23名成员都是从波士顿儿童医院传染病部和哈佛大学其他机构的五个附属单位中挑选出来的有成就的研究者和经验丰富的导师。在研究导师和方案指导委员会的指导下，在微生物发病机制、宿主反应和疫苗或流行病学和卫生政策这三大调查领域之一为每位学员设计了个性化课程。流行病学和卫生政策途径的学员有机会获得哈佛大学公共卫生学院的公共卫生硕士学位，这是培训计划的一个组成部分。其他途径的学员还接受流行病学、生物统计学、临床试验设计和分析方法方面的培训。所有的受训者都有研讨会和指导，在拨款准备和科学写作，以补充指导的研究经验。为每位受训者任命一个奖学金监督委员会，以监督其进展并提供职业指导。在第二年或第三年，学员将在全国会议上展示他们的工作，准备一份或多份手稿供出版，在大多数情况下，申请K08或其他职业发展奖，以支持他们作为一名独立的研究者过渡。相关性：培训计划的目标是培养儿科医生和博士博士后科学家的职业生涯，研究人员将解决当前和未来儿童感染的挑战。迫切需要训练有素的儿科传染病调查人员来应对先天性艾滋病毒感染、儿童疟疾和结核病、腹泻疾病和呼吸道感染等对儿童健康的持续和新出现的威胁，这些严重问题因抗菌素耐药性的增加和社会对儿童疫苗的反对而进一步复杂化。