Basic research training in embryonic development

描述(由申请人提供)：俄勒冈健康与科学大学(OHSU)的生物医学研究在过去十年中得到了相当大的发展，作为这一增长的一部分，以胚胎发育为主要重点的实验室数量大幅增加。为了支持这些实验室的培训工作，提交这份修订后的申请是为了支持一个基础研究培训计划，该计划将为博士后和博士后学生提供发育生物学分子和细胞方面的严格基础。拟议的培训人员由23名研究人员组成，他们利用生化、分子、细胞和/或遗传学方法了解各种脊椎动物和无脊椎动物模型系统的发育过程，包括苍蝇、小鸡、青蛙、鱼和老鼠。该计划的教职员工来自医学院内的基础科学系和独立研究单位，全部设在OHSU主校区。所有培训教员都有积极的、外部资助的基础研究计划。发育生物学领域正日益与细胞生物学和其他学科交织在一起，要求学生接受不同学科的广泛教育，以应对未来的挑战。为了实现这一目标，所有学员将在教师实验室接受严格的胚胎发育研究培训，并将参加期刊俱乐部、研讨会和科学会议，包括西北地区发展生物学会议、年度学员研讨会和OHSU研究生静修活动。博士前实习生还将接受生物化学、遗传学、细胞生物学、分子生物学和神经生物学的广泛课堂教育，以及通过包括讲座和实验室练习的正式课程进行更深入的发育生物学培训。OHSU培训计划的一个突出特点是，具有不同研究兴趣和专业知识的教职员工之间存在着高度的互动和合作。

DESCRIPTION (provided by applicant): Biomedical research at the Oregon Health and Science University (OHSU) has expanded considerable over the past decade and, as part of this growth, the number of laboratories with a primary focus in embryonic development has increased greatly. To support the training efforts of these laboratories, this revised application is submitted to support a basic research training program that will provide predoctoral and postdoctoral students with a rigorous grounding in molecular and cellular aspects of Developmental Biology. The proposed training faculty is comprised of 23 investigators who utilize biochemical, molecular, cellular, and/or genetic approaches to understanding developmental processes in a variety of vertebrate and invertebrate animal model systems including flies, chick, frog, fish, and mouse. Program faculty are drawn from basic science departments and independent research units within the School of Medicine, all housed on the main OHSU campus. All members of the training faculty have active, externally funded basic research programs. The field of Developmental Biology is becoming increasingly intertwined with cell biology and other disciplines, requiring that students receive a broad education in diverse subjects in order to meet future challenges. To accomplish this, all trainees will receive rigorous research training in embryonic development in their preceptors' laboratories, and will participate in journal clubs, seminars, and scientific meetings, including the Northwest Regional Developmental Biology Meeting, the annual trainees symposium, and the OHSU graduate student retreat. Predoctoral trainees will also receive a broad classroom based education in biochemistry, genetics, cell biology, molecular biology, and neurobiology, as well as more in depth training in developmental biology through formal coursework involving both lectures and laboratory exercises. One outstanding feature of the training program at OHSU is the high level of interactions and collaborations that occur among faculty members with diverse research interests and expertise.