TISSUE AND BLOOED PROCUREMENT

组织和血液采购共享资源 艾伦·D·普罗亚，医学博士和拉杰什·C·达什，医学博士 这个共享资源的目标是开发一个立即冷冻的、石蜡包埋的肿瘤样本库 综合癌症中心使用的样本和相应的血液成分 调查人员。组织标本将以统一的方式制备，包括肿瘤和非肿瘤 如有可能，将从每个受试者身上制备样本。临床数据将被抽象为可搜索的 数据库，其中还将包含组织标本和摘要的显微摄影图像 病理数据。将收集纵向临床数据，这将允许使用组织获得数据 血液样本要与治疗结果和临床结果相关联。所有主要计划中的 癌症中心依赖于人类肿瘤样本，这一共享资源将提供大量的 开发基因组和蛋白质组技术所需的样本。患者治疗前后的血液样本 肿瘤切除将使癌症中心的研究人员能够开发新的检测和监测方法 癌症。

TISSUE AND BLOOD PROCUREMENT SHARED RESOURCE Alan D. Proia, M.D., Ph.D. and Rajesh C. Dash, M.D., Co-Directors The goal of this Shared Resource is to develop a bank of immediately frozen tumor samples, paraffinembedded samples and corresponding blood components for use by Comprehensive Cancer Center investigators. Tissue specimens will be prepared in a uniform manner, and both neoplastic and non-neoplastic samples will be prepared from each subject, when possible. Clinical data will be abstracted into a searchable database, which will also contain photomicrographic images of the tissue specimens and abstracted pathological data. Longitudinal clinical data will be collected, which will allow data obtained using the tissue and blood samples to be correlated with results of therapy and clinical outcomes. All major programs in the Cancer Center rely on human tumor samples, and this Shared Resource will provide the large numbers of samples needed to exploit genomic and proteomic technologies. Blood samples from patients before and after tumor resection will allow Cancer Center investigators to develop new methods for detecting and monitoring cancers.