Molecular basis of T cell Receptor bias in viral immunity
Molecular basis of T cell Receptor bias in viral immunity
批准号:
nhmrc : 508929
负责人:
Dr Craig Clements
金额:
$36.01万
依托单位国家:
澳大利亚
项目类别:
NHMRC Project Grants
财政年份:
2008
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2008-01-01 至 2011-12-31
中文摘要
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英文摘要
Viral infection results in the activation and proliferation of T cells that eradicate infected cells. Recognition of infected cells is meditated by presentation and recognition of viral protein fragments via specific cell surface receptors. This proposal plans to examine the factors that determine the diversity of the immune response and the consequences of such diversity on anti-viral immunity. This has implications for the development of vaccines.
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