CA: Administrative Core

CA：行政核心

• 批准号: 7510676
• 负责人: SCOTT M LIPPMAN
• 金额: $ 10.64万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7510676
• 关键词: Achievement; Address; Advisory Committees; Award; Biological Markers; Biometry; Budgets; Cancer Center; Clinical; Clinical Trials; Closure; Collaborations; Communication; Consultations; Data; Development; Discipline; Employment; Ensure; Funding; Goals; Grant; Head and Neck Cancer; Human Resources; Laboratories; Leadership; Minority; Monitor; National Cancer Institute; Organ; Pathology; Policies; Preparation; Procedures; Process; Publications; Quality Control; Regulation; Reporting; Reproduction spores; Research; Research Personnel; Resources; Risk; Role; Schedule; Site; Tissue Procurements; Translations; United States National Institutes of Health; Woman; anticancer research; base; career; clinical application; cost; data management; experience; falls; interdisciplinary approach; lectures; programs; success; symposium

Core A is essential to the success of the SPORE and provides oversight and support of all SPORE projects and activities; ensures compliance with all general, governmental, and National Cancer Institute (NCI)/National Institutes of Health (NIH) regulations and requirements; coordinates communications and consultations with the NCI project officer and other NCI staff in preparing all required reports and publications; coordinates all SPORE-related meetings and communications of the Executive Committee, Internal and External Advisory Boards, the Biostatistics and Data Management Core (Core B), and the Tissue Procurement, Pathology and Biomarker Core (Core C); and other key functions. Over the previous grant period, Core A oversaw the annual budget/rebudget development, distribution, and oversight of grant funds; supported the Executive Committee and advisory boards in scheduling and coordinating regularly scheduled meetings and ad hoc consultations; coordinated the annual solicitation, review, and award process for the Career Development and the Developmental Research Programs; served as the primary liaison in developing potential InterSPORE collaborations and with the NCI SPORE program representatives; and interacted on a regular basis with Core Directors and Project Leaders to review progress, identify problems, and resolve issues hampering successful achievement of their aims. The past trial activation and accrual record of this HN SPORE was the appropriate target of criticism in our previous review; thus, the SPORE leadership team has implemented several mechanisms to enhance the oversight, and thus activation and accrual, of our SPORE clinical trials, including 1) quarterly accrual report submissions to the Executive Committee (and more frequently should concerns arise); quarterly presentations by the Pis of the SPORE trials to the Executive Committee on accrual progress; annual review of all trials by the Internal and External Advisory Boards; and a requirement to address accrual deficiencies within six-months or risk study closure or replacement. Major SPORE and Core A leadership changes occurred in the fall of 2006, when Dr. Scott M. Lippman succeeded Dr. Waun Ki Hong as SPORE PI and Core A Director and Dr. Rakesh Kumar succeeded Dr. Reuben Lotan as a SPORE Co-Pi and Core A Co-Director (sharing these roles with Dr. Gary L. dayman, who continues a Co-Pi and Co-Director from the previous grant period). The experienced leadership of the HN SPORE will ensure full compliance with all policies and procedures required of NCIand NIH-funded research programs to successfully achieve the SPORE's overall aims.

核心A对于孢子的成功至关重要，并提供对所有孢子项目的监督和支持 和活动；确保遵守所有一般，政府和国家癌症研究所 （NCI）/国立卫生研究院（NIH）法规和要求；协调通信和 与NCI项目官员和其他NCI工作人员进行磋商，以准备所有必需的报告和 出版物；协调执行委员会的所有与孢子有关的会议和沟通 内部和外部咨询委员会，生物统计学和数据管理核心（核心B）以及 组织采购，病理和生物标志物核心（核心C）；和其他关键功能。在上一个 授予期，核心A监督年度预算/斥责开发，分配和赠款的监督 资金;支持执行委员会和咨询委员会定期安排和协调 预定会议和临时咨询；协调年度招标，审查和奖励 职业发展和发展研究计划的过程；担任主要 与NCI孢子计划代表建立潜在的散布合作的联络； 并与核心董事和项目负责人定期进行互动以审查进度，确定 问题，并解决阻碍成功实现目标的问题。过去的试验激活和 在我们之前的评论中，此HN孢子的应计记录是批评的适当目标。因此， 孢子领导团队已经实施了多种机制来增强监督，从而 激活和应计的孢子临床试验，包括1）季度应计报告提交给 执行委员会（并且应该更频繁地出现担忧）； PIS的季度演示 对执行委员会的孢子试验；内部和所有试验的年度审查 外部咨询委员会；以及在六个月内解决应计的缺陷或风险研究的要求 关闭或更换。主要的孢子和核心A领导力变化发生在2006年秋天，当时博士博士。 Scott M. Lippman接替Waun Ki Hong博士担任Spore Pi和Core A主任和Rakesh Kumar博士 接替鲁本·洛丹（Reuben Lotan）博士为孢子的共同副驾驶和核心联合导演（与加里（Gary）博士分享这些角色 L. Dayman，从上一个赠款期开始继续担任Co-Pi和联合导演）。经验丰富的 HN孢子的领导将确保完全遵守NCIAND要求的所有政策和程序 NIH资助的研究计划成功实现了孢子的整体目标。