CA: Administrative Core

CA：行政核心

• 批准号: 7510676
• 负责人: SCOTT M LIPPMAN
• 金额: $ 10.64万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-08-01 至 2013-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7510676
• 关键词: Achievement; Address; Advisory Committees; Award; Biological Markers; Biometry; Budgets; Cancer Center; Clinical; Clinical Trials; Closure; Collaborations; Communication; Consultations; Data; Development; Discipline; Employment; Ensure; Funding; Goals; Grant; Head and Neck Cancer; Human Resources; Laboratories; Leadership; Minority; Monitor; National Cancer Institute; Organ; Pathology; Policies; Preparation; Procedures; Process; Publications; Quality Control; Regulation; Reporting; Reproduction spores; Research; Research Personnel; Resources; Risk; Role; Schedule; Site; Tissue Procurements; Translations; United States National Institutes of Health; Woman; anticancer research; base; career; clinical application; cost; data management; experience; falls; interdisciplinary approach; lectures; programs; success; symposium

Core A is essential to the success of the SPORE and provides oversight and support of all SPORE projects and activities; ensures compliance with all general, governmental, and National Cancer Institute (NCI)/National Institutes of Health (NIH) regulations and requirements; coordinates communications and consultations with the NCI project officer and other NCI staff in preparing all required reports and publications; coordinates all SPORE-related meetings and communications of the Executive Committee, Internal and External Advisory Boards, the Biostatistics and Data Management Core (Core B), and the Tissue Procurement, Pathology and Biomarker Core (Core C); and other key functions. Over the previous grant period, Core A oversaw the annual budget/rebudget development, distribution, and oversight of grant funds; supported the Executive Committee and advisory boards in scheduling and coordinating regularly scheduled meetings and ad hoc consultations; coordinated the annual solicitation, review, and award process for the Career Development and the Developmental Research Programs; served as the primary liaison in developing potential InterSPORE collaborations and with the NCI SPORE program representatives; and interacted on a regular basis with Core Directors and Project Leaders to review progress, identify problems, and resolve issues hampering successful achievement of their aims. The past trial activation and accrual record of this HN SPORE was the appropriate target of criticism in our previous review; thus, the SPORE leadership team has implemented several mechanisms to enhance the oversight, and thus activation and accrual, of our SPORE clinical trials, including 1) quarterly accrual report submissions to the Executive Committee (and more frequently should concerns arise); quarterly presentations by the Pis of the SPORE trials to the Executive Committee on accrual progress; annual review of all trials by the Internal and External Advisory Boards; and a requirement to address accrual deficiencies within six-months or risk study closure or replacement. Major SPORE and Core A leadership changes occurred in the fall of 2006, when Dr. Scott M. Lippman succeeded Dr. Waun Ki Hong as SPORE PI and Core A Director and Dr. Rakesh Kumar succeeded Dr. Reuben Lotan as a SPORE Co-Pi and Core A Co-Director (sharing these roles with Dr. Gary L. dayman, who continues a Co-Pi and Co-Director from the previous grant period). The experienced leadership of the HN SPORE will ensure full compliance with all policies and procedures required of NCIand NIH-funded research programs to successfully achieve the SPORE's overall aims.

核心A对SPORE的成功至关重要，并为所有SPORE项目提供监督和支持 和活动;确保遵守所有一般，政府和国家癌症研究所 (NCI)/美国国立卫生研究院（NIH）的法规和要求;协调通信和 与NCI项目官员和其他NCI工作人员协商准备所有必要的报告， 出版物;协调执行委员会所有与SPORE有关的会议和通信， 内部和外部咨询委员会、生物统计和数据管理核心（核心B）以及 组织采购、病理学和生物标志物核心（核心C）;以及其他关键职能。比上一 在赠款期间，核心A监督年度预算/再预算的制定、分配和赠款的监督 支持执行委员会和咨询委员会定期安排和协调 安排会议和临时磋商;协调年度招标、评审和授予 职业发展和发展研究计划的过程;担任主要的 在发展潜在的InterSPORE合作方面以及与NCI SPORE计划代表进行联络; 并定期与核心主管和项目负责人互动，以审查进展情况， 问题，并解决阻碍成功实现其目标的问题。过去的试验激活和 在我们之前的审查中，该HN SPORE的应计记录是批评的适当目标;因此， SPORE领导团队实施了若干机制来加强监督， 我们的SPORE临床试验的激活和应计费用，包括1）向 执行委员会（如果出现关切，则更频繁）; 向执行委员会报告应计进展情况;由内部审计委员会对所有试验进行年度审查， 外部咨询委员会;并要求在六个月或风险研究内解决应计缺陷 关闭或更换。主要的孢子和核心A的领导层变化发生在2006年秋季，当博士。 斯科特·M Lippman接替Waun Ki Hong博士担任SPORE PI和Core A总监，Rakesh Kumar博士 接替Reuben Lotan博士担任SPORE Co-Pi和Core A Co-Director（与加里博士共同担任这些职务 L. dayman，谁继续从上一个赠款期的共同PI和共同董事）。有经验的 HN SPORE的领导层将确保完全遵守NCIand要求的所有政策和程序 NIH资助的研究项目，以成功实现SPORE的总体目标。