Developmental Research Program

发展研究计划的主要目标是资助有希望的早期项目，这些项目 解决预防、早期发现和治疗胰腺癌的重要翻译目标 癌症。我们发展研究计划的主要目的是带来新颖的翻译研究 孢子计划的项目。决定该计划优先顺序的关键因素是创新， 在转化性胰腺癌研究中的新颖性和成功潜力。所有发展基金将 根据提交的NIH风格的试点项目申请，通过竞争获得奖励。有一个 要求提供清晰的证据，证明拟议的项目具有发展为更大研究的潜力 该项目将涉及人类对胰腺癌的干预(诊断或治疗)。我们会有 每年至少可获得175,000美元(孢子补助金每年100,000美元，匹配每年75,000美元 来自UNMC/Eppley癌症中心的资金)，这将用于资助2个项目。我们会接受 来自单一调查人员的申请，用于预算高达87,500美元或更高的重点项目 涉及两名或更多调查人员的合作项目，预算高达175,000美元。建议书是 由管理核心接收和处理。每年一次的征求建议书(RFP)是 由首席研究员开发并分发给内布拉斯加医学大学的所有教职员工 克雷顿大学，内布拉斯加大学奥马哈分校，内布拉斯加大学林肯分校， 内布拉斯加大学卡尼分校，其他机构的合作教员，以及其他机构的教职员工 已与我们联系或已被孢子科学理事会确认的机构，内部 顾问委员会，或外部顾问委员会，作为现有项目或开发人员的潜在合作者 与胰腺癌相关的重要新孢子项目。将征集两种类型的申请。 来自单一调查人员的申请，适用于每年预算高达87,500美元或更高的重点项目 涉及两名或更多调查人员的协作翻译项目，每个调查人员的预算最高可达175,000美元 年。申请由一个研究部门审查，该部门由内部咨询委员会、 没有冲突的孢子计划，从UNMC Eppley癌症中心挑选的科学家和临床医生 中心。资助申请的最终选择由外部咨询委员会作出，该委员会担任 咨询委员会，与布拉坦博士和格雷姆博士协商，他们是 发展研究计划。受资助的项目必须有一套可量化的里程碑 在第一年结束时取得可以接受的进展的成就。

The principal goal of the Developmental Research Program is to fund promising early stage projects that address important translational objectives in prevention, early detection, and therapy of pancreatic carcinoma. Our principal intent for Developmental Research Program is to bring novel translational research projects to the SPORE program. Key elements that determine priority in this program are innovation, novelty, and potential for success in translational pancreatic cancer research. All Developmental Funds will be awarded by competition based on submission of a NIH-style pilot project application. There is a requirement for clear evidence that the proposed project shows potential of developing into a larger research project that will involve human intervention for pancreatic cancer (diagnostic or therapeutic). We will have available a minimum of $175,000 a year ($100,000 from the SPORE grant and $75,000 a year in matching funds from the UNMC/Eppley Cancer Center), which will be used to fund 2 projects. We will accept applications from single investigators for focused projects with budgets of up to $87,500 or larger collaborative projects involving two or more investigators with budgets of up to $175,000. Proposals are received and processed by the Administrative Core. Once a year, a request for proposals (RFP) is developed by the Principal Investigator and distributed to all faculty at the University of Nebraska Medical Center, Creighton University, the University of Nebraska at Omaha, the University of Nebraska at Lincoln, University of Nebraska at Kearny, collaborating faculty at other institutions, and faculty members at other Institutions who have contacted us or have been identified by the SPORE Scientific Council, Internal Advisory Board, or External Advisory Committee as potential collaborators on existing projects or developers of important new SPORE projects related to pancreatic cancer. Two types of applications will be solicited. Applications from single investigators for focused projects with budgets of up to $87,500 per year, or larger collaborative translational projects involving two or more investigators with budgets of up to $175,000 per year. Applications are reviewed by a study section comprised of the Internal Advisory Board, members of the SPORE program who are not in conflict, selected scientists and clinicians from the UNMC Eppley Cancer Center. Final selection of the funded applications is made by the External Advisory Board, who acts as a Advisory Council, in consultation with Dr. Brattain and Dr. Grem, who are the administrative leaders of the Developmental Research Program. Funded projects must have a set of quantifiable milestones for achievement that represent acceptable progress by the end of the first year.