Developmental Research Program

发展研究计划

• 批准号: 8328172
• 负责人: MICHAEL G BRATTAIN
• 金额: $ 7.85万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2011
• 资助国家: 美国
• 起止时间: 2011-09-01 至 2013-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8328172
• 关键词: Achievement; Address; Advisory Committees; Award; Basic Science; Budgets; Cancer Diagnostics; Conflict (Psychology); Consultations; Development; Early Diagnosis; Elements; Faculty; Funding; Goals; Grant; Human; Institution; Intervention; Malignant neoplasm of gastrointestinal tract; Malignant neoplasm of pancreas; Medical center; Nebraska; Nursing Faculty; Pancreatic carcinoma; Pilot Projects; Prevention; Principal Investigator; Process; Request for Proposals; Research; Research Personnel; Research Project Grants; Scientist; Staging; Study Section; Therapeutic; Time; Translational Research; UNMC Eppley Cancer Center; United States National Institutes of Health; Universities; Wages; anticancer research; base; innovation; member; novel; programs; success

The principal goal of the Developmental Research Program is to fund promising early stage projects that address important translational objectives in prevention, early detection, and therapy of pancreatic carcinoma. Our principal intent for Developmental Research Program is to bring novel translational research projects to the SPORE program. Key elements that determine priority in this program are innovation, novelty, and potential for success in translational pancreatic cancer research. All Developmental Funds will be awarded by competition based on submission of a NIH-style pilot project application. There is a requirement for clear evidence that the proposed project shows potential of developing into a larger research project that will involve human intervention for pancreatic cancer (diagnostic or therapeutic). We will have available a minimum of $175,000 a year ($100,000 from the SPORE grant and $75,000 a year in matching funds from the UNMC/Eppley Cancer Center), which will be used to fund 2 projects. We will accept applications from single investigators for focused projects with budgets of up to $87,500 or larger collaborative projects involving two or more investigators with budgets of up to $175,000. Proposals are received and processed by the Administrative Core. Once a year, a request for proposals (RFP) is developed by the Principal Investigator and distributed to all faculty at the University of Nebraska Medical Center, Creighton University, the University of Nebraska at Omaha, the University of Nebraska at Lincoln, University of Nebraska at Kearny, collaborating faculty at other institutions, and faculty members at other Institutions who have contacted us or have been identified by the SPORE Scientific Council, Internal Advisory Board, or External Advisory Committee as potential collaborators on existing projects or developers of important new SPORE projects related to pancreatic cancer. Two types of applications will be solicited. Applications from single investigators for focused projects with budgets of up to $87,500 per year, or larger collaborative translational projects involving two or more investigators with budgets of up to $175,000 per year. Applications are reviewed by a study section comprised of the Internal Advisory Board, members of the SPORE program who are not in conflict, selected scientists and clinicians from the UNMC Eppley Cancer Center. Final selection of the funded applications is made by the External Advisory Board, who acts as a Advisory Council, in consultation with Dr. Brattain and Dr. Grem, who are the administrative leaders of the Developmental Research Program. Funded projects must have a set of quantifiable milestones for achievement that represent acceptable progress by the end of the first year.

发展研究计划的主要目标是资助有前途的早期项目， 在胰腺癌的预防、早期发现和治疗中， carcinoma.我们的发展研究计划的主要目的是带来新的转化研究 项目的SPORE计划。决定该计划优先事项的关键因素是创新， 新奇，并在转化胰腺癌研究中取得成功的潜力。所有发展基金将 根据提交NIH风格的试点项目申请通过竞争获奖。有一个 要求提供明确的证据，证明拟议的项目具有发展成为更大规模研究的潜力 该项目将涉及对胰腺癌的人为干预（诊断或治疗）。我们会一起 每年最低175，000美元（100，000美元来自SPORE赠款，每年75，000美元用于匹配 联合国医学委员会/埃普利癌症中心提供的资金），将用于资助2个项目。我们将接受 预算不超过87 500美元的重点项目的单个调查员的申请 涉及两名或两名以上调查员的合作项目，预算最高为175 000美元。建议是 由行政核心接收和处理。每年一次，征求建议书（RFP） 由主要研究者制定并分发给内布拉斯加大学医学院的所有教职员工 中心，克雷顿大学，内布拉斯加大学奥马哈分校，内布拉斯加大学林肯分校， 内布拉斯加大学科尔尼分校，其他机构的合作教师，以及其他机构的教师 已与我们联系或已被SPORE科学理事会内部 顾问委员会或外部顾问委员会作为现有项目或开发人员的潜在合作者 与胰腺癌有关的重要新的孢子项目。将征集两类申请。 单个调查员对每年预算不超过87 500美元的重点项目提出的申请 涉及两名或更多研究人员的协作翻译项目，每个项目的预算高达175，000美元 年申请由一个研究科审查，该科由内部咨询委员会、 SPORE计划没有冲突，选择了来自UNMC Eppley Cancer的科学家和临床医生 中心资助申请的最终选择由外部咨询委员会作出，该委员会作为 咨询理事会，与联合国人权事务高级专员办事处的行政领导人Brattain博士和Grem博士协商， 发展研究计划。受资助的项目必须有一套可量化的里程碑， 在第一年年底之前取得代表可接受进展的成就。