Biostatistics and Bioinformatics Core

生物统计核心的目的是为孢子项目提供设计和分析支持， 发展项目，以及其他核心。这一核心有三个具体目标。 1.提供生物统计学专业知识，以规划、实施、分析和报告实验室、动物、 孢子项目和发展项目的临床和流行病学研究。生物统计学的核心 将与孢子研究人员就协议和实验设计进行合作，并将提供 样本量和统计能力。该核心将就监测的最佳方法向研究人员提供建议 正在进行的研究。核心将提供已完成的实验的统计分析，并参与 手稿准备工作。 2.提供或建议支持计算基础设施，包括计算机数据库， 统计计算机包、公共可用的统计程序和计算机之间的数据共享或 数据库。由于有效的信息学基础设施对孢子的功能至关重要，因此 生物统计核心将致力于确保存储和访问由生物统计中心使用和生成的数据 孢子是高效和有效的。生物统计核心将支持数据资源的高效管理 就数据库设计提供咨询，帮助设计有效的数据收集方法并进行审计 数据质量。 3：为孢子研究人员提供咨询和统计教育。除了正式协作 通过努力，生物统计核心将可用于与研究人员进行持续的非正式磋商 孢子的持续时间。 此外，生物统计核心将与DF/HCC皮肤癌孢子内的调查人员合作，其他 皮肤癌孢子和合作组织试图建立一个预后和预测模型 黑色素瘤患者使用基于网络的统计产品，将帮助医生定义预后和 为不同阶段的黑色素瘤患者选择最佳的治疗方法。

The purpose of the Biostatistics Core is to provide design and analytic support to SPORE Projects, Developmental Projects, and other Cores. This core has three specific aims. 1. To provide biostatistical expertise for the planning, conduct, analysis, and reporting of laboratory, animal, clinical, and epidemiological studies for SPORE projects and developmental projects. The Biostatistics Core will work with SPORE researchers on protocol and experimental design, and will provide estimates of sample size and statistical power. The Core will advise researchers about optimal methods for monitoring ongoing studies. The Core will provide statistical analyses of completed experiments, and participate in manuscript preparation. 2. To provide or recommend supporting computational infrastructure, including computer databases, statistical computer packages, publicly available statistical programs and data sharing between computers or databases. Because an effective informatics infrastructure is critical to the functioning of the SPORE, the Biostatistics Core will work to assure that the storage and accessibility of data used and generated by the SPORE is efficient and effective. The Biostatistics Core will support efficient management of data resources by consulting on database design, helping to design efficient data collection methods and conducting audits of data quality. 3: To provide consulting and statistical education to SPORE researchers. In addition to formal collaborative efforts, the Biostatistics Core will be available for ongoing, informal consultation with researchers over the duration of the SPORE. In addition the Biostatistics Core will work with investigators within the DF/HCC Skin Cancer SPORE, other Skin Cancer SPOREs and Cooperative Groups to attempt to build a prognostic and predictive model for melanoma patients with a web-based statistical product that will help physicians define the prognosis and select the optimal therapy for individual patients with various stages of melanoma.