Molecular epidemiology of infection in aboriginal communities

已知牙龈组织的破坏性疾病受到修饰因素的深刻影响，所述修饰因素包括全身性疾病如糖尿病、社会经济状况和缺乏对牙龈边缘处的微生物积累的有效控制。这项调查将研究的假设，数量有限的致病性细菌菌株，定量分子探针分析定义，坚持或重新感染的个人，以保持高疾病负担的不利修改因素的存在下，流行于孤立的，处境不利的土著社区。

Destructive diseases of the gum tissue are known to be profoundly affected by modifying factors including systemic diseases such as diabetes, socio-economic conditions and the lack of effective control of microbial accumulation at the gum margin. This investigation will examine the hypothesis that a limited number of pathogenic bacterial strains, defined by quantitative molecular probe analysis, persist in or re-infect individuals to maintain a high disease burden in the presence of adverse modifying factors that prevail in isolated, disadvantaged Aboriginal communities.