Molecular epidemiology of infection in aboriginal communities

原住民社区感染的分子流行病学

• 批准号: nhmrc : 219185
• 负责人: A/Pr Fjelda Martin
• 金额: $ 9.94万
• 依托单位国家: 澳大利亚
• 项目类别: NHMRC Strategic Awards
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-01-01 至 2005-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/molecular-epidemiology-infection-aboriginal-communities/76344
• 关键词: Molecular; epidemiology; infection; aboriginal; communities

Destructive diseases of the gum tissue are known to be profoundly affected by modifying factors including systemic diseases such as diabetes, socio-economic conditions and the lack of effective control of microbial accumulation at the gum margin. This investigation will examine the hypothesis that a limited number of pathogenic bacterial strains, defined by quantitative molecular probe analysis, persist in or re-infect individuals to maintain a high disease burden in the presence of adverse modifying factors that prevail in isolated, disadvantaged Aboriginal communities.

已知牙龈组织的破坏性疾病受到修饰因素的深刻影响，所述修饰因素包括全身性疾病如糖尿病、社会经济状况和缺乏对牙龈边缘处的微生物积累的有效控制。这项调查将研究的假设，数量有限的致病性细菌菌株，定量分子探针分析定义，坚持或重新感染的个人，以保持高疾病负担的不利修改因素的存在下，流行于孤立的，处境不利的土著社区。