NJ Medical School Request for Autoclave and Tunnel Washer

新泽西州医学院要求高压灭菌器和隧道式清洗机

• 批准号: 7629283
• 负责人: Bruce Adam Scharf
• 金额: $ 50万
• 依托单位: UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-08-28 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7629283
• 关键词: Cancer Center; Dentistry; Dimensions; Equipment; Faculty; Funding; Future; Laboratory Animal Production and Facilities; Medical; Medicine; Mus; New Jersey; Principal Investigator; Research; Research Infrastructure; Research Personnel; Science; Transgenic Mice; United States National Institutes of Health; Universities; Walking; animal facility; disorder prevention; medical schools; meetings

DESCRIPTION (provided by applicant): The University of Medicine and Dentistry of New Jersey (UMDNJ), Newark urgently requests funds to purchase a Tunnel Washer and Large Walk-in Sterilizer so we can clean and sterilize our rapidly expanding numbers of mouse cages at the Transgenic Mouse Barrier Facility (TgMBF) and Central Research Animal Facilities (CRAF) in our Medical Sciences Building (MSB). Since 1998 the number of mice and associated caging infrastructure has almost tripled in the MSB with no concurrent improvements to the existing cage wash facility. Without the requested equipment, NIH-funded research at the MSB may undergo significant delays as Principal Investigators will be unable to maintain their mice colonies in numbers sufficient to conduct current studies or to expand and increase these colonies to meet future needs. The proposed Tunnel Washer will enable us to wash 3,283 more cages daily and the proposed Large Walk-in Sterilizer will enable us to sterilize 525 more cages each day. Previous submissions to NIH requesting funds for a cage wash facility at the TgMBF were well received but ultimately not funded. The only cage wash facility at the MSB is at the CRAF. Although the Cancer Center Animal Facility at UMDNJ does have a large walk-in sterilizer and tunnel washer, logistical distance, proper disease prevention and more importantly a growing heavy wash load at the CCAF itself precludes the TgMBF and CRAF from sending cages to the CCAF for cleaning. Replacing outdated non-functional equipment at the CRAF cage wash facility with a new Tunnel Washer and Large Walk-in Sterilizer will enable us to greatly enhance our ability to support the large number of NIH funded investigators currently using our facility. This equipment upgrade fits existing facility dimensions and the required renovations to existing infrastructure will be partially funded by the NJMS. Without a new Tunnel Washer and Large Walk-in Sterilizer our facility will not meet the basic needs of the numbers of mice necessary for our faculty to properly conduct their NIH funded research.

描述(由申请人提供)：新泽西医学与牙科大学(UMDNJ)，纽瓦克紧急申请资金购买隧道垫圈和大型步入式消毒器，以便我们可以清洁和消毒我们在我们的医学大楼(MSB)的转基因小鼠屏障设施(TgMBF)和中央研究动物设施(CRAF)迅速增加的老鼠笼子。自1998年以来，MSB的老鼠数量和相关的笼子基础设施几乎增加了两倍，而现有的笼子清洗设施并没有同时得到改善。如果没有所需的设备，NIH资助的MSB研究可能会经历重大延误，因为首席调查人员将无法维持足够数量的小鼠群体来进行当前的研究，或扩大和增加这些群体以满足未来的需求。拟议的隧道洗涤器可让我们每天多清洗3,283个笼子，而拟议的大型步入式消毒器可让我们每天多为525个笼子消毒。之前向NIH提交的为TgMBF的笼子清洗设施提供资金的申请很受欢迎，但最终没有获得资金。MSB唯一的笼子清洗设施在CRAF。虽然UMDNJ的癌症中心动物设施确实有一个大型的步入式消毒器和隧道垫圈，但后勤距离、适当的疾病预防以及CCAF本身日益沉重的洗涤负担使TgMBF和CRAF无法将笼子送到CCAF进行清洁。用新的隧道垫圈和大型步入式灭菌器取代CRAF笼子清洗设施中过时的非功能性设备，将使我们能够极大地增强我们支持目前使用我们设施的NIH资助的大量调查人员的能力。这次设备升级符合现有设施的规模，对现有基础设施所需的翻新将由NJMS提供部分资金。如果没有新的隧道洗衣机和大型步入式灭菌器，我们的设施将无法满足教职员工正确开展NIH资助的研究所需的小鼠数量的基本需求。